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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC6A7
All Species:
25.76
Human Site:
Y529
Identified Species:
51.52
UniProt:
Q99884
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99884
NP_055043.2
636
70893
Y529
Q
P
S
E
Y
G
S
Y
R
F
P
P
W
A
E
Chimpanzee
Pan troglodytes
XP_527072
813
89904
Y706
Q
P
S
E
Y
G
S
Y
R
F
P
P
W
A
E
Rhesus Macaque
Macaca mulatta
Q9MYX0
630
70239
K526
T
Q
F
C
R
D
V
K
E
M
L
G
F
S
P
Dog
Lupus familis
XP_546305
590
65600
W488
G
S
Y
R
F
P
A
W
A
E
L
L
G
I
L
Cat
Felis silvestris
Mouse
Mus musculus
Q6PGE7
637
71047
Y529
Q
P
S
E
Y
G
S
Y
R
F
P
A
W
A
E
Rat
Rattus norvegicus
P28573
637
71072
Y529
Q
P
S
E
Y
G
S
Y
R
F
P
A
W
A
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510332
626
69635
Y519
Q
P
S
E
Y
G
N
Y
H
F
P
F
W
A
E
Chicken
Gallus gallus
XP_414596
636
71287
Y528
Q
P
S
E
Y
G
S
Y
R
F
P
A
W
A
E
Frog
Xenopus laevis
A7Y2W8
633
71004
Y526
R
P
I
Q
Y
N
D
Y
L
Y
P
D
W
A
I
Zebra Danio
Brachydanio rerio
NP_001009557
786
87171
S684
L
T
F
I
L
A
L
S
L
Y
Q
W
K
V
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VR07
943
103618
G827
H
E
P
T
Y
H
N
G
R
Y
T
Y
P
D
W
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q03614
615
69247
Y512
M
G
F
R
P
G
N
Y
W
K
F
C
W
S
C
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
77.8
42.2
89.7
N.A.
97.8
97.8
N.A.
84.5
86.7
46.3
41.3
N.A.
28.8
N.A.
38.3
N.A.
Protein Similarity:
100
77.9
60.8
91
N.A.
98.4
98.5
N.A.
91
93
66
56.8
N.A.
41.1
N.A.
59.2
N.A.
P-Site Identity:
100
100
0
0
N.A.
93.3
93.3
N.A.
80
93.3
40
0
N.A.
13.3
N.A.
20
N.A.
P-Site Similarity:
100
100
13.3
20
N.A.
93.3
93.3
N.A.
86.6
93.3
60
6.6
N.A.
26.6
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
9
9
0
9
0
0
25
0
59
0
% A
% Cys:
0
0
0
9
0
0
0
0
0
0
0
9
0
0
9
% C
% Asp:
0
0
0
0
0
9
9
0
0
0
0
9
0
9
0
% D
% Glu:
0
9
0
50
0
0
0
0
9
9
0
0
0
0
50
% E
% Phe:
0
0
25
0
9
0
0
0
0
50
9
9
9
0
0
% F
% Gly:
9
9
0
0
0
59
0
9
0
0
0
9
9
0
0
% G
% His:
9
0
0
0
0
9
0
0
9
0
0
0
0
0
0
% H
% Ile:
0
0
9
9
0
0
0
0
0
0
0
0
0
9
9
% I
% Lys:
0
0
0
0
0
0
0
9
0
9
0
0
9
0
0
% K
% Leu:
9
0
0
0
9
0
9
0
17
0
17
9
0
0
9
% L
% Met:
9
0
0
0
0
0
0
0
0
9
0
0
0
0
9
% M
% Asn:
0
0
0
0
0
9
25
0
0
0
0
0
0
0
0
% N
% Pro:
0
59
9
0
9
9
0
0
0
0
59
17
9
0
9
% P
% Gln:
50
9
0
9
0
0
0
0
0
0
9
0
0
0
0
% Q
% Arg:
9
0
0
17
9
0
0
0
50
0
0
0
0
0
0
% R
% Ser:
0
9
50
0
0
0
42
9
0
0
0
0
0
17
0
% S
% Thr:
9
9
0
9
0
0
0
0
0
0
9
0
0
0
0
% T
% Val:
0
0
0
0
0
0
9
0
0
0
0
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
9
9
0
0
9
67
0
9
% W
% Tyr:
0
0
9
0
67
0
0
67
0
25
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _