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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ASCL2 All Species: 24.24
Human Site: S149 Identified Species: 48.48
UniProt: Q99929 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99929 NP_005161.1 193 20185 S149 S P S R A S S S P G R G G S S
Chimpanzee Pan troglodytes XP_521719 193 20195 S149 S P S R A S S S P G R G G S S
Rhesus Macaque Macaca mulatta XP_001117240 565 59543 S521 S P S R A S S S P G R G G S S
Dog Lupus familis XP_540787 308 31819 S264 S P S C A S S S P G R G G S S
Cat Felis silvestris
Mouse Mus musculus O35885 263 27766 S219 S C A S T S P S P D R L G C S
Rat Rattus norvegicus P19360 260 27677 S217 S L S C T S T S P D R L G C S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506820 235 25615 F183 H D A V S A A F Q A G V L S P
Chicken Gallus gallus Q08856 258 28438 W177 A D S R S P V W P A R G S S F
Frog Xenopus laevis Q06234 199 22356 F147 H D A V S A A F Q S G V L S P
Zebra Danio Brachydanio rerio Q90260 195 22097 S151 A Y S A G P E S P H S A Y S S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P10083 201 22735 S154 S Y C K P A T S T I P G A T P
Honey Bee Apis mellifera XP_001120320 295 31316 S247 S P T P S F V S E A S S A G S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 32.5 56.8 N.A. 56.2 54.6 N.A. 22.9 24 50.2 41.5 N.A. 25.8 30.8 N.A. N.A.
Protein Similarity: 100 98.9 33.2 56.8 N.A. 59.3 59.2 N.A. 41.2 32.5 61.3 52.8 N.A. 41.7 39.3 N.A. N.A.
P-Site Identity: 100 100 100 93.3 N.A. 46.6 53.3 N.A. 6.6 40 6.6 33.3 N.A. 20 26.6 N.A. N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 53.3 60 N.A. 33.3 53.3 33.3 40 N.A. 46.6 40 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 17 0 25 9 34 25 17 0 0 25 0 9 17 0 0 % A
% Cys: 0 9 9 17 0 0 0 0 0 0 0 0 0 17 0 % C
% Asp: 0 25 0 0 0 0 0 0 0 17 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 9 0 9 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 9 0 17 0 0 0 0 0 0 9 % F
% Gly: 0 0 0 0 9 0 0 0 0 34 17 50 50 9 0 % G
% His: 17 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % I
% Lys: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 9 0 0 0 0 0 0 0 0 0 17 17 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 42 0 9 9 17 9 0 67 0 9 0 0 0 25 % P
% Gln: 0 0 0 0 0 0 0 0 17 0 0 0 0 0 0 % Q
% Arg: 0 0 0 34 0 0 0 0 0 0 59 0 0 0 0 % R
% Ser: 67 0 59 9 34 50 34 75 0 9 17 9 9 67 67 % S
% Thr: 0 0 9 0 17 0 17 0 9 0 0 0 0 9 0 % T
% Val: 0 0 0 17 0 0 17 0 0 0 0 17 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % W
% Tyr: 0 17 0 0 0 0 0 0 0 0 0 0 9 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _