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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DUSP9 All Species: 10.91
Human Site: S16 Identified Species: 20
UniProt: Q99956 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99956 NP_001386.1 384 41868 S16 L W L R R E L S P P R P R L L
Chimpanzee Pan troglodytes XP_001142865 966 103249 I112 G Y E V P T L I P P P K Q Q S
Rhesus Macaque Macaca mulatta XP_001084096 384 41947 S16 L W L R R E L S P P R P R L L
Dog Lupus familis XP_549360 625 66368 S261 L W L R R A L S P P R P R L L
Cat Felis silvestris
Mouse Mus musculus Q91Z46 368 40502 A15 W L Q E E L E A R G G A S L L
Rat Rattus norvegicus Q64346 381 42300 E28 A W L N E Q L E L G N E Q L L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506331 383 42666 A17 P R A P M A A A M P C K S A E
Chicken Gallus gallus Q9PW71 375 41034 V19 G S A L R R L V G R E E A S G
Frog Xenopus laevis NP_001083256 378 42018 S20 M A L G K S V S W L N E Q L D
Zebra Danio Brachydanio rerio NP_956068 364 40382 E11 K S A E W L Q E D L Q A G G G
Tiger Blowfish Takifugu rubipres P0C599 210 23683
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q10038 657 70984 R19 C G L A A L I R E A P D T T L
Sea Urchin Strong. purpuratus XP_794377 403 44845 Q29 S S K S V Q E Q V L S G Q V L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 35.7 98.4 56.3 N.A. 53.1 52.8 N.A. 52.5 36.2 52.3 53.9 22.6 N.A. N.A. 20 44.9
Protein Similarity: 100 37.3 99.2 57.9 N.A. 64.8 65 N.A. 65.3 51.8 65.8 66.1 34.6 N.A. N.A. 31.3 57
P-Site Identity: 100 20 100 93.3 N.A. 13.3 33.3 N.A. 6.6 13.3 20 0 0 N.A. N.A. 13.3 6.6
P-Site Similarity: 100 33.3 100 93.3 N.A. 20 46.6 N.A. 13.3 13.3 46.6 6.6 0 N.A. N.A. 20 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 24 8 8 16 8 16 0 8 0 16 8 8 0 % A
% Cys: 8 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 8 0 0 8 0 0 8 % D
% Glu: 0 0 8 16 16 16 16 16 8 0 8 24 0 0 8 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 16 8 0 8 0 0 0 0 8 16 8 8 8 8 16 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 8 8 0 0 0 0 0 0 0 % I
% Lys: 8 0 8 0 8 0 0 0 0 0 0 16 0 0 0 % K
% Leu: 24 8 47 8 0 24 47 0 8 24 0 0 0 47 54 % L
% Met: 8 0 0 0 8 0 0 0 8 0 0 0 0 0 0 % M
% Asn: 0 0 0 8 0 0 0 0 0 0 16 0 0 0 0 % N
% Pro: 8 0 0 8 8 0 0 0 31 39 16 24 0 0 0 % P
% Gln: 0 0 8 0 0 16 8 8 0 0 8 0 31 8 0 % Q
% Arg: 0 8 0 24 31 8 0 8 8 8 24 0 24 0 0 % R
% Ser: 8 24 0 8 0 8 0 31 0 0 8 0 16 8 8 % S
% Thr: 0 0 0 0 0 8 0 0 0 0 0 0 8 8 0 % T
% Val: 0 0 0 8 8 0 8 8 8 0 0 0 0 8 0 % V
% Trp: 8 31 0 0 8 0 0 0 8 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _