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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DUSP9
All Species:
15.15
Human Site:
S325
Identified Species:
27.78
UniProt:
Q99956
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99956
NP_001386.1
384
41868
S325
D
L
V
K
R
K
K
S
N
I
S
P
N
F
N
Chimpanzee
Pan troglodytes
XP_001142865
966
103249
S907
D
L
V
K
R
K
K
S
N
I
S
P
N
F
N
Rhesus Macaque
Macaca mulatta
XP_001084096
384
41947
S325
D
L
V
K
R
K
K
S
N
I
S
P
N
F
N
Dog
Lupus familis
XP_549360
625
66368
S566
D
L
V
K
R
K
K
S
N
I
S
P
N
F
N
Cat
Felis silvestris
Mouse
Mus musculus
Q91Z46
368
40502
V310
L
N
D
A
Y
D
F
V
K
R
K
K
S
N
I
Rat
Rattus norvegicus
Q64346
381
42300
V323
M
N
D
A
Y
D
I
V
K
M
K
K
S
N
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506331
383
42666
Q312
V
T
V
A
Y
L
M
Q
K
M
N
L
S
L
N
Chicken
Gallus gallus
Q9PW71
375
41034
Q314
Q
L
L
Q
F
E
S
Q
V
L
A
T
S
C
A
Frog
Xenopus laevis
NP_001083256
378
42018
I319
S
M
N
D
A
Y
D
I
V
K
M
K
K
S
N
Zebra Danio
Brachydanio rerio
NP_956068
364
40382
V306
L
N
D
A
Y
D
F
V
K
R
K
K
S
N
I
Tiger Blowfish
Takifugu rubipres
P0C599
210
23683
A152
R
S
A
T
L
V
L
A
Y
L
M
M
E
H
S
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10038
657
70984
T475
S
T
P
I
L
N
F
T
N
P
C
F
N
S
P
Sea Urchin
Strong. purpuratus
XP_794377
403
44845
T333
T
S
P
C
R
T
G
T
C
R
C
A
I
D
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
35.7
98.4
56.3
N.A.
53.1
52.8
N.A.
52.5
36.2
52.3
53.9
22.6
N.A.
N.A.
20
44.9
Protein Similarity:
100
37.3
99.2
57.9
N.A.
64.8
65
N.A.
65.3
51.8
65.8
66.1
34.6
N.A.
N.A.
31.3
57
P-Site Identity:
100
100
100
100
N.A.
0
0
N.A.
13.3
6.6
6.6
0
0
N.A.
N.A.
13.3
6.6
P-Site Similarity:
100
100
100
100
N.A.
6.6
13.3
N.A.
33.3
46.6
13.3
6.6
20
N.A.
N.A.
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
31
8
0
0
8
0
0
8
8
0
0
8
% A
% Cys:
0
0
0
8
0
0
0
0
8
0
16
0
0
8
0
% C
% Asp:
31
0
24
8
0
24
8
0
0
0
0
0
0
8
0
% D
% Glu:
0
0
0
0
0
8
0
0
0
0
0
0
8
0
0
% E
% Phe:
0
0
0
0
8
0
24
0
0
0
0
8
0
31
0
% F
% Gly:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
0
0
8
0
0
8
8
0
31
0
0
8
0
24
% I
% Lys:
0
0
0
31
0
31
31
0
31
8
24
31
8
0
0
% K
% Leu:
16
39
8
0
16
8
8
0
0
16
0
8
0
8
0
% L
% Met:
8
8
0
0
0
0
8
0
0
16
16
8
0
0
0
% M
% Asn:
0
24
8
0
0
8
0
0
39
0
8
0
39
24
47
% N
% Pro:
0
0
16
0
0
0
0
0
0
8
0
31
0
0
8
% P
% Gln:
8
0
0
8
0
0
0
16
0
0
0
0
0
0
0
% Q
% Arg:
8
0
0
0
39
0
0
0
0
24
0
0
0
0
0
% R
% Ser:
16
16
0
0
0
0
8
31
0
0
31
0
39
16
8
% S
% Thr:
8
16
0
8
0
8
0
16
0
0
0
8
0
0
0
% T
% Val:
8
0
39
0
0
8
0
24
16
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
31
8
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _