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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DUSP9 All Species: 9.39
Human Site: Y122 Identified Species: 17.22
UniProt: Q99956 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99956 NP_001386.1 384 41868 Y122 E E G Y L A Y Y L Q G G F S R
Chimpanzee Pan troglodytes XP_001142865 966 103249 S704 V S R P H A L S P T G G F S R
Rhesus Macaque Macaca mulatta XP_001084096 384 41947 Y122 E E G Y L A Y Y L Q G G F S R
Dog Lupus familis XP_549360 625 66368 A363 L R E E G Y L A Y Y L Q G G F
Cat Felis silvestris
Mouse Mus musculus Q91Z46 368 40502 L107 A S V L G L L L Q K L R D D G
Rat Rattus norvegicus Q64346 381 42300 K120 S V L G L L L K K L K D E G C
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506331 383 42666 W109 Y D E A T A E W Q Q D S G A P
Chicken Gallus gallus Q9PW71 375 41034 V111 D D S T V A L V L R A L R R D
Frog Xenopus laevis NP_001083256 378 42018 L116 A G E S V L G L L M K R L K D
Zebra Danio Brachydanio rerio NP_956068 364 40382 L103 S A G S V L G L L M Q K L R D
Tiger Blowfish Takifugu rubipres P0C599 210 23683
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q10038 657 70984 L272 G I S R S P T L A I S Y I M R
Sea Urchin Strong. purpuratus XP_794377 403 44845 Y130 E V G Y R V S Y L R G G F S E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 35.7 98.4 56.3 N.A. 53.1 52.8 N.A. 52.5 36.2 52.3 53.9 22.6 N.A. N.A. 20 44.9
Protein Similarity: 100 37.3 99.2 57.9 N.A. 64.8 65 N.A. 65.3 51.8 65.8 66.1 34.6 N.A. N.A. 31.3 57
P-Site Identity: 100 40 100 0 N.A. 0 6.6 N.A. 13.3 13.3 6.6 13.3 0 N.A. N.A. 6.6 60
P-Site Similarity: 100 40 100 0 N.A. 6.6 6.6 N.A. 33.3 40 13.3 20 0 N.A. N.A. 6.6 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 16 8 0 8 0 39 0 8 8 0 8 0 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % C
% Asp: 8 16 0 0 0 0 0 0 0 0 8 8 8 8 24 % D
% Glu: 24 16 24 8 0 0 8 0 0 0 0 0 8 0 8 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 31 0 8 % F
% Gly: 8 8 31 8 16 0 16 0 0 0 31 31 16 16 8 % G
% His: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 0 0 0 0 0 0 0 8 0 0 8 0 0 % I
% Lys: 0 0 0 0 0 0 0 8 8 8 16 8 0 8 0 % K
% Leu: 8 0 8 8 24 31 39 31 47 8 16 8 16 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 16 0 0 0 8 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 8 0 8 0 0 8 0 0 0 0 0 8 % P
% Gln: 0 0 0 0 0 0 0 0 16 24 8 8 0 0 0 % Q
% Arg: 0 8 8 8 8 0 0 0 0 16 0 16 8 16 31 % R
% Ser: 16 16 16 16 8 0 8 8 0 0 8 8 0 31 0 % S
% Thr: 0 0 0 8 8 0 8 0 0 8 0 0 0 0 0 % T
% Val: 8 16 8 0 24 8 0 8 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 24 0 8 16 24 8 8 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _