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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DUSP9
All Species:
9.39
Human Site:
Y81
Identified Species:
17.22
UniProt:
Q99956
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99956
NP_001386.1
384
41868
Y81
P
P
A
P
V
L
L
Y
D
Q
G
G
G
R
R
Chimpanzee
Pan troglodytes
XP_001142865
966
103249
W467
R
A
H
T
L
L
V
W
E
P
Q
K
G
Q
G
Rhesus Macaque
Macaca mulatta
XP_001084096
384
41947
Y81
P
P
A
P
V
L
L
Y
D
Q
G
G
G
R
R
Dog
Lupus familis
XP_549360
625
66368
Y326
P
P
A
P
V
L
L
Y
D
Q
G
G
G
R
P
Cat
Felis silvestris
Mouse
Mus musculus
Q91Z46
368
40502
A74
H
A
D
K
E
R
F
A
T
R
C
K
A
A
T
Rat
Rattus norvegicus
Q64346
381
42300
T87
C
E
D
R
D
R
F
T
R
R
C
G
T
D
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506331
383
42666
P76
R
L
K
K
G
N
L
P
I
R
S
I
I
P
N
Chicken
Gallus gallus
Q9PW71
375
41034
R78
L
P
A
E
G
E
V
R
A
R
L
R
A
G
L
Frog
Xenopus laevis
NP_001083256
378
42018
R82
L
F
A
C
G
E
D
R
D
K
F
A
R
R
C
Zebra Danio
Brachydanio rerio
NP_956068
364
40382
E70
I
P
N
N
E
D
K
E
K
F
V
K
R
C
K
Tiger Blowfish
Takifugu rubipres
P0C599
210
23683
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10038
657
70984
V134
D
K
F
R
S
V
M
V
L
E
G
G
F
K
Q
Sea Urchin
Strong. purpuratus
XP_794377
403
44845
A91
K
D
L
F
V
K
M
A
S
K
V
P
L
I
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
35.7
98.4
56.3
N.A.
53.1
52.8
N.A.
52.5
36.2
52.3
53.9
22.6
N.A.
N.A.
20
44.9
Protein Similarity:
100
37.3
99.2
57.9
N.A.
64.8
65
N.A.
65.3
51.8
65.8
66.1
34.6
N.A.
N.A.
31.3
57
P-Site Identity:
100
13.3
100
93.3
N.A.
0
6.6
N.A.
6.6
13.3
20
6.6
0
N.A.
N.A.
13.3
6.6
P-Site Similarity:
100
46.6
100
93.3
N.A.
6.6
13.3
N.A.
13.3
26.6
26.6
13.3
0
N.A.
N.A.
46.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
39
0
0
0
0
16
8
0
0
8
16
8
0
% A
% Cys:
8
0
0
8
0
0
0
0
0
0
16
0
0
8
8
% C
% Asp:
8
8
16
0
8
8
8
0
31
0
0
0
0
8
0
% D
% Glu:
0
8
0
8
16
16
0
8
8
8
0
0
0
0
0
% E
% Phe:
0
8
8
8
0
0
16
0
0
8
8
0
8
0
0
% F
% Gly:
0
0
0
0
24
0
0
0
0
0
31
39
31
8
8
% G
% His:
8
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
0
0
0
8
0
0
8
8
8
0
% I
% Lys:
8
8
8
16
0
8
8
0
8
16
0
24
0
8
8
% K
% Leu:
16
8
8
0
8
31
31
0
8
0
8
0
8
0
16
% L
% Met:
0
0
0
0
0
0
16
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
8
0
8
0
0
0
0
0
0
0
0
8
% N
% Pro:
24
39
0
24
0
0
0
8
0
8
0
8
0
8
8
% P
% Gln:
0
0
0
0
0
0
0
0
0
24
8
0
0
8
8
% Q
% Arg:
16
0
0
16
0
16
0
16
8
31
0
8
16
31
16
% R
% Ser:
0
0
0
0
8
0
0
0
8
0
8
0
0
0
0
% S
% Thr:
0
0
0
8
0
0
0
8
8
0
0
0
8
0
16
% T
% Val:
0
0
0
0
31
8
16
8
0
0
16
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
24
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _