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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FOXC2
All Species:
22.42
Human Site:
S219
Identified Species:
44.85
UniProt:
Q99958
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99958
NP_005242.1
501
53719
S219
V
I
K
S
E
A
A
S
P
A
L
P
V
I
T
Chimpanzee
Pan troglodytes
XP_523450
676
72856
Y348
L
V
K
P
P
Y
S
Y
I
A
L
I
T
M
A
Rhesus Macaque
Macaca mulatta
XP_001085933
501
53645
S219
V
I
K
S
E
A
A
S
P
A
L
P
V
I
T
Dog
Lupus familis
XP_860948
505
53975
S219
V
I
K
S
E
A
A
S
P
A
L
P
V
I
T
Cat
Felis silvestris
Mouse
Mus musculus
Q61850
494
52856
S218
V
V
K
S
E
A
A
S
P
A
L
P
V
I
T
Rat
Rattus norvegicus
NP_001095150
494
52836
S218
V
V
K
S
E
A
A
S
P
A
L
P
V
I
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_990469
468
50649
S206
L
P
K
E
A
S
S
S
S
S
S
S
S
A
S
Frog
Xenopus laevis
Q9PVY9
465
51595
K203
E
L
P
K
H
E
K
K
I
V
I
K
S
E
S
Zebra Danio
Brachydanio rerio
NP_571803
476
52154
D213
S
Q
P
V
R
I
Q
D
I
K
T
E
N
G
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P32027
508
54498
H214
H
M
A
A
H
A
A
H
F
K
K
E
P
L
M
Honey Bee
Apis mellifera
XP_001121752
495
55049
L218
G
T
K
K
L
A
S
L
E
T
T
L
C
K
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780709
519
57235
G240
V
V
C
T
G
E
M
G
D
S
S
I
N
R
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
45.4
99.1
95.8
N.A.
89.6
90
N.A.
N.A.
66.8
65.8
52.8
N.A.
32.8
31.1
N.A.
37.5
Protein Similarity:
100
52.9
99.4
96.4
N.A.
92.4
92.8
N.A.
N.A.
72.4
75.6
65.8
N.A.
42.7
43.3
N.A.
49.5
P-Site Identity:
100
20
100
100
N.A.
93.3
93.3
N.A.
N.A.
13.3
0
6.6
N.A.
13.3
13.3
N.A.
6.6
P-Site Similarity:
100
46.6
100
100
N.A.
100
100
N.A.
N.A.
46.6
20
6.6
N.A.
33.3
20
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
9
9
59
50
0
0
50
0
0
0
9
9
% A
% Cys:
0
0
9
0
0
0
0
0
0
0
0
0
9
0
0
% C
% Asp:
0
0
0
0
0
0
0
9
9
0
0
0
0
0
9
% D
% Glu:
9
0
0
9
42
17
0
0
9
0
0
17
0
9
0
% E
% Phe:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% F
% Gly:
9
0
0
0
9
0
0
9
0
0
0
0
0
9
0
% G
% His:
9
0
0
0
17
0
0
9
0
0
0
0
0
0
0
% H
% Ile:
0
25
0
0
0
9
0
0
25
0
9
17
0
42
0
% I
% Lys:
0
0
67
17
0
0
9
9
0
17
9
9
0
9
0
% K
% Leu:
17
9
0
0
9
0
0
9
0
0
50
9
0
9
0
% L
% Met:
0
9
0
0
0
0
9
0
0
0
0
0
0
9
9
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
17
0
0
% N
% Pro:
0
9
17
9
9
0
0
0
42
0
0
42
9
0
9
% P
% Gln:
0
9
0
0
0
0
9
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
9
0
0
0
0
0
0
0
0
9
0
% R
% Ser:
9
0
0
42
0
9
25
50
9
17
17
9
17
0
17
% S
% Thr:
0
9
0
9
0
0
0
0
0
9
17
0
9
0
50
% T
% Val:
50
34
0
9
0
0
0
0
0
9
0
0
42
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
9
0
9
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _