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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FOXC2
All Species:
23.94
Human Site:
Y339
Identified Species:
47.88
UniProt:
Q99958
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99958
NP_005242.1
501
53719
Y339
S
M
R
A
M
S
L
Y
T
G
A
E
R
P
A
Chimpanzee
Pan troglodytes
XP_523450
676
72856
Y514
S
M
R
A
M
S
L
Y
T
G
A
E
R
P
A
Rhesus Macaque
Macaca mulatta
XP_001085933
501
53645
Y339
S
M
R
A
M
S
L
Y
T
G
A
E
R
P
A
Dog
Lupus familis
XP_860948
505
53975
Y339
S
M
R
A
M
S
L
Y
T
G
A
E
R
P
A
Cat
Felis silvestris
Mouse
Mus musculus
Q61850
494
52856
Y338
S
M
R
A
M
S
L
Y
T
G
A
E
R
P
A
Rat
Rattus norvegicus
NP_001095150
494
52836
Y338
S
M
R
A
M
S
L
Y
T
G
A
E
R
P
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_990469
468
50649
A322
Q
P
S
G
Y
S
A
A
C
S
Q
A
L
D
T
Frog
Xenopus laevis
Q9PVY9
465
51595
Q319
M
D
T
S
G
S
Y
Q
C
T
M
R
A
M
S
Zebra Danio
Brachydanio rerio
NP_571803
476
52154
S329
S
V
Y
S
S
P
C
S
Q
N
S
I
S
T
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P32027
508
54498
I340
S
G
H
S
P
T
T
I
S
T
P
H
G
P
A
Honey Bee
Apis mellifera
XP_001121752
495
55049
H340
G
L
Q
H
P
H
P
H
S
H
S
I
M
T
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780709
519
57235
V367
T
C
S
K
R
P
V
V
S
S
L
N
Q
Y
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
45.4
99.1
95.8
N.A.
89.6
90
N.A.
N.A.
66.8
65.8
52.8
N.A.
32.8
31.1
N.A.
37.5
Protein Similarity:
100
52.9
99.4
96.4
N.A.
92.4
92.8
N.A.
N.A.
72.4
75.6
65.8
N.A.
42.7
43.3
N.A.
49.5
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
6.6
6.6
6.6
N.A.
20
0
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
6.6
20
26.6
N.A.
40
40
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
50
0
0
9
9
0
0
50
9
9
0
59
% A
% Cys:
0
9
0
0
0
0
9
0
17
0
0
0
0
0
0
% C
% Asp:
0
9
0
0
0
0
0
0
0
0
0
0
0
9
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
50
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
9
0
9
9
0
0
0
0
50
0
0
9
0
0
% G
% His:
0
0
9
9
0
9
0
9
0
9
0
9
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
9
0
0
0
17
0
0
0
% I
% Lys:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
9
0
0
0
0
50
0
0
0
9
0
9
0
0
% L
% Met:
9
50
0
0
50
0
0
0
0
0
9
0
9
9
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
9
0
9
0
0
0
% N
% Pro:
0
9
0
0
17
17
9
0
0
0
9
0
0
59
0
% P
% Gln:
9
0
9
0
0
0
0
9
9
0
9
0
9
0
9
% Q
% Arg:
0
0
50
0
9
0
0
0
0
0
0
9
50
0
0
% R
% Ser:
67
0
17
25
9
67
0
9
25
17
17
0
9
0
17
% S
% Thr:
9
0
9
0
0
9
9
0
50
17
0
0
0
17
17
% T
% Val:
0
9
0
0
0
0
9
9
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
9
0
9
50
0
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _