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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FOXC2
All Species:
17.27
Human Site:
Y488
Identified Species:
34.55
UniProt:
Q99958
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.45
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99958
NP_005242.1
501
53719
Y488
Y
R
S
T
P
P
L
Y
R
H
A
A
P
Y
S
Chimpanzee
Pan troglodytes
XP_523450
676
72856
Y663
Y
R
S
T
P
S
L
Y
R
H
A
A
P
Y
S
Rhesus Macaque
Macaca mulatta
XP_001085933
501
53645
Y488
Y
R
S
T
P
S
L
Y
R
H
A
A
P
Y
S
Dog
Lupus familis
XP_860948
505
53975
Y492
Y
R
S
T
P
S
L
Y
R
H
A
A
P
Y
S
Cat
Felis silvestris
Mouse
Mus musculus
Q61850
494
52856
R482
R
A
T
P
S
L
Y
R
H
A
A
P
Y
S
Y
Rat
Rattus norvegicus
NP_001095150
494
52836
R482
R
A
T
P
S
L
Y
R
H
A
A
P
Y
S
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_990469
468
50649
R456
N
S
A
P
S
L
Y
R
H
T
A
P
Y
S
Y
Frog
Xenopus laevis
Q9PVY9
465
51595
R453
R
S
A
P
S
I
Y
R
H
S
S
P
Y
A
Y
Zebra Danio
Brachydanio rerio
NP_571803
476
52154
Y463
F
P
P
S
Q
P
I
Y
R
T
S
G
A
F
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P32027
508
54498
G481
A
A
L
S
G
N
L
G
Q
L
G
Q
L
S
N
Honey Bee
Apis mellifera
XP_001121752
495
55049
K480
D
P
S
L
V
Y
V
K
Q
E
W
I
P
C
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780709
519
57235
Y506
G
S
T
P
A
S
M
Y
P
P
S
A
H
Y
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
45.4
99.1
95.8
N.A.
89.6
90
N.A.
N.A.
66.8
65.8
52.8
N.A.
32.8
31.1
N.A.
37.5
Protein Similarity:
100
52.9
99.4
96.4
N.A.
92.4
92.8
N.A.
N.A.
72.4
75.6
65.8
N.A.
42.7
43.3
N.A.
49.5
P-Site Identity:
100
93.3
93.3
93.3
N.A.
6.6
6.6
N.A.
N.A.
6.6
0
20
N.A.
6.6
13.3
N.A.
26.6
P-Site Similarity:
100
93.3
93.3
93.3
N.A.
13.3
13.3
N.A.
N.A.
13.3
13.3
53.3
N.A.
26.6
33.3
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
25
17
0
9
0
0
0
0
17
59
42
9
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% C
% Asp:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% E
% Phe:
9
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% F
% Gly:
9
0
0
0
9
0
0
9
0
0
9
9
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
34
34
0
0
9
0
0
% H
% Ile:
0
0
0
0
0
9
9
0
0
0
0
9
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% K
% Leu:
0
0
9
9
0
25
42
0
0
9
0
0
9
0
0
% L
% Met:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
0
0
0
9
0
0
0
0
0
0
0
0
9
% N
% Pro:
0
17
9
42
34
17
0
0
9
9
0
34
42
0
0
% P
% Gln:
0
0
0
0
9
0
0
0
17
0
0
9
0
0
0
% Q
% Arg:
25
34
0
0
0
0
0
34
42
0
0
0
0
0
0
% R
% Ser:
0
25
42
17
34
34
0
0
0
9
25
0
0
34
42
% S
% Thr:
0
0
25
34
0
0
0
0
0
17
0
0
0
0
9
% T
% Val:
0
0
0
0
9
0
9
0
0
0
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% W
% Tyr:
34
0
0
0
0
9
34
50
0
0
0
0
34
42
34
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _