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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PKP2 All Species: 13.03
Human Site: S693 Identified Species: 28.67
UniProt: Q99959 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99959 NP_004563 881 97399 S693 Y L S L I A K S V R N Y T Q E
Chimpanzee Pan troglodytes XP_514090 747 82870 K560 L N L M G K S K K D A T L E A
Rhesus Macaque Macaca mulatta XP_001107663 191 21019
Dog Lupus familis XP_543739 836 92715 S648 Y L S L I A K S V R N Y T Q E
Cat Felis silvestris
Mouse Mus musculus P97350 728 80878 K541 N L M G K S K K D A T L E A C
Rat Rattus norvegicus NP_001093969 795 87809 S608 L S L I A K S S R N Y T Q E A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518983 211 23819 T24 S E A L Q T L T D N M I I P F
Chicken Gallus gallus XP_416362 957 104212 S769 Y L S L I A K S T R N Y T Q E
Frog Xenopus laevis NP_001085350 799 88799 N612 L S L I A K S N R N Y T Q E A
Zebra Danio Brachydanio rerio NP_001106904 815 90749 T627 L S L I A V S T N Q H T K Q A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9U308 1254 138340 S982 L K L L Q D S S N I E T L E A
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 28.1 21.4 85.1 N.A. 31.2 75 N.A. 20.6 38.7 49.7 32.3 N.A. N.A. N.A. 20.1 N.A.
Protein Similarity: 100 45.4 21.5 88.6 N.A. 46.8 81.8 N.A. 22.9 53.9 65.1 51.8 N.A. N.A. N.A. 35.5 N.A.
P-Site Identity: 100 0 0 100 N.A. 13.3 6.6 N.A. 6.6 93.3 0 6.6 N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: 100 13.3 0 100 N.A. 20 20 N.A. 20 93.3 20 33.3 N.A. N.A. N.A. 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 28 28 0 0 0 10 10 0 0 10 46 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % C
% Asp: 0 0 0 0 0 10 0 0 19 10 0 0 0 0 0 % D
% Glu: 0 10 0 0 0 0 0 0 0 0 10 0 10 37 28 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % F
% Gly: 0 0 0 10 10 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % H
% Ile: 0 0 0 28 28 0 0 0 0 10 0 10 10 0 0 % I
% Lys: 0 10 0 0 10 28 37 19 10 0 0 0 10 0 0 % K
% Leu: 46 37 46 46 0 0 10 0 0 0 0 10 19 0 0 % L
% Met: 0 0 10 10 0 0 0 0 0 0 10 0 0 0 0 % M
% Asn: 10 10 0 0 0 0 0 10 19 28 28 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % P
% Gln: 0 0 0 0 19 0 0 0 0 10 0 0 19 37 0 % Q
% Arg: 0 0 0 0 0 0 0 0 19 28 0 0 0 0 0 % R
% Ser: 10 28 28 0 0 10 46 46 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 10 0 19 10 0 10 46 28 0 0 % T
% Val: 0 0 0 0 0 10 0 0 19 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 28 0 0 0 0 0 0 0 0 0 19 28 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _