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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SH3GL1
All Species:
17.88
Human Site:
Y255
Identified Species:
43.7
UniProt:
Q99961
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99961
NP_003016.1
368
41490
Y255
S
S
R
P
K
R
E
Y
K
P
K
P
R
E
P
Chimpanzee
Pan troglodytes
XP_001138821
389
42936
Y276
S
S
R
P
K
R
E
Y
K
P
K
P
R
E
P
Rhesus Macaque
Macaca mulatta
XP_001101957
348
39144
Y235
S
S
R
P
R
R
E
Y
K
P
K
P
R
E
P
Dog
Lupus familis
XP_854499
368
41462
Y255
S
S
R
P
K
R
E
Y
K
P
K
P
R
E
P
Cat
Felis silvestris
Mouse
Mus musculus
Q62419
368
41500
F255
S
S
R
P
K
R
E
F
K
P
R
P
R
E
P
Rat
Rattus norvegicus
O35964
368
41473
F255
S
S
R
P
R
R
E
F
K
P
R
P
Q
E
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519054
377
41950
V267
V
S
Q
L
S
A
L
V
E
A
Q
L
D
Y
H
Chicken
Gallus gallus
Q8AXV0
367
41714
Y255
S
S
R
P
R
R
E
Y
K
P
K
P
R
E
T
Frog
Xenopus laevis
NP_001085149
366
41411
F255
S
S
R
P
R
R
E
F
K
P
K
P
R
E
S
Zebra Danio
Brachydanio rerio
NP_958905
351
39753
L236
A
V
Q
I
L
D
E
L
S
D
K
L
R
D
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
77.6
87.5
97.2
N.A.
94
92.9
N.A.
74.2
91.3
83.9
75.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
82
89.4
98.6
N.A.
97.2
97.2
N.A.
79
95.6
93.7
88.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
100
N.A.
86.6
73.3
N.A.
6.6
86.6
80
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
26.6
93.3
93.3
40
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
10
0
0
0
10
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
10
0
0
0
10
0
0
10
10
0
% D
% Glu:
0
0
0
0
0
0
90
0
10
0
0
0
0
80
0
% E
% Phe:
0
0
0
0
0
0
0
30
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
40
0
0
0
80
0
70
0
0
0
0
% K
% Leu:
0
0
0
10
10
0
10
10
0
0
0
20
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
80
0
0
0
0
0
80
0
80
0
0
60
% P
% Gln:
0
0
20
0
0
0
0
0
0
0
10
0
10
0
0
% Q
% Arg:
0
0
80
0
40
80
0
0
0
0
20
0
80
0
10
% R
% Ser:
80
90
0
0
10
0
0
0
10
0
0
0
0
0
10
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% T
% Val:
10
10
0
0
0
0
0
10
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
50
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _