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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SH3GL2
All Species:
23.94
Human Site:
S278
Identified Species:
58.52
UniProt:
Q99962
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99962
NP_003017.1
352
39962
S278
T
Q
P
N
G
G
L
S
H
T
G
T
P
K
P
Chimpanzee
Pan troglodytes
XP_520501
541
59195
S467
T
Q
P
N
G
G
L
S
H
T
G
T
P
K
P
Rhesus Macaque
Macaca mulatta
XP_001102732
556
61817
S482
T
Q
P
N
G
G
L
S
H
T
G
T
P
K
P
Dog
Lupus familis
XP_853971
385
42906
S311
T
Q
P
N
G
G
L
S
H
T
G
T
P
K
P
Cat
Felis silvestris
Mouse
Mus musculus
Q62420
352
39937
S278
T
Q
P
N
G
G
L
S
H
T
G
T
P
K
P
Rat
Rattus norvegicus
O35179
352
39881
S278
T
Q
P
N
G
G
L
S
H
T
G
T
P
K
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q8AXV1
353
39916
I278
N
T
Q
H
N
G
G
I
S
H
A
T
T
P
K
Frog
Xenopus laevis
NP_001088944
353
40080
I278
N
S
Q
Y
N
G
G
I
S
L
A
G
T
P
K
Zebra Danio
Brachydanio rerio
NP_957410
347
38974
P278
G
S
I
G
H
S
G
P
S
R
S
P
A
P
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VU84
531
58711
T435
V
R
T
K
V
S
V
T
V
Q
Q
S
Q
S
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
65
63.1
87.2
N.A.
98.8
98.5
N.A.
N.A.
90.3
85.8
74.7
N.A.
21
N.A.
N.A.
N.A.
Protein Similarity:
100
65
63.3
88.8
N.A.
99.1
99.1
N.A.
N.A.
96
92.9
88.3
N.A.
38.2
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
13.3
6.6
0
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
20
6.6
0
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
20
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
10
60
80
30
0
0
0
60
10
0
0
0
% G
% His:
0
0
0
10
10
0
0
0
60
10
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
0
20
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
10
0
0
0
0
0
0
0
0
0
60
20
% K
% Leu:
0
0
0
0
0
0
60
0
0
10
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
20
0
0
60
20
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
60
0
0
0
0
10
0
0
0
10
60
30
60
% P
% Gln:
0
60
20
0
0
0
0
0
0
10
10
0
10
0
0
% Q
% Arg:
0
10
0
0
0
0
0
0
0
10
0
0
0
0
0
% R
% Ser:
0
20
0
0
0
20
0
60
30
0
10
10
0
10
0
% S
% Thr:
60
10
10
0
0
0
0
10
0
60
0
70
20
0
0
% T
% Val:
10
0
0
0
10
0
10
0
10
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _