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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SH3GL2
All Species:
24.55
Human Site:
Y299
Identified Species:
60
UniProt:
Q99962
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99962
NP_003017.1
352
39962
Y299
Q
P
C
C
R
A
L
Y
D
F
E
P
E
N
E
Chimpanzee
Pan troglodytes
XP_520501
541
59195
Y488
Q
P
C
C
R
A
L
Y
D
F
E
P
E
N
E
Rhesus Macaque
Macaca mulatta
XP_001102732
556
61817
Y503
Q
P
C
C
R
A
L
Y
D
F
E
P
E
N
E
Dog
Lupus familis
XP_853971
385
42906
Y332
Q
P
C
C
R
A
L
Y
D
F
E
P
E
N
E
Cat
Felis silvestris
Mouse
Mus musculus
Q62420
352
39937
Y299
Q
P
C
C
R
A
L
Y
D
F
E
P
E
N
E
Rat
Rattus norvegicus
O35179
352
39881
Y299
Q
P
C
C
R
A
L
Y
D
F
E
P
E
N
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q8AXV1
353
39916
L299
D
Q
P
C
C
R
A
L
Y
D
F
E
P
E
N
Frog
Xenopus laevis
NP_001088944
353
40080
L299
D
Q
P
C
C
R
S
L
Y
D
F
D
P
E
N
Zebra Danio
Brachydanio rerio
NP_957410
347
38974
E299
A
L
Y
D
F
D
P
E
N
E
G
E
L
G
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VU84
531
58711
T456
T
L
E
R
N
A
L
T
D
L
V
N
E
D
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
65
63.1
87.2
N.A.
98.8
98.5
N.A.
N.A.
90.3
85.8
74.7
N.A.
21
N.A.
N.A.
N.A.
Protein Similarity:
100
65
63.3
88.8
N.A.
99.1
99.1
N.A.
N.A.
96
92.9
88.3
N.A.
38.2
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
6.6
6.6
0
N.A.
26.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
6.6
6.6
6.6
N.A.
40
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
70
10
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
60
80
20
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
20
0
0
10
0
10
0
0
70
20
0
10
0
10
10
% D
% Glu:
0
0
10
0
0
0
0
10
0
10
60
20
70
20
60
% E
% Phe:
0
0
0
0
10
0
0
0
0
60
20
0
0
0
10
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
10
0
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
20
0
0
0
0
70
20
0
10
0
0
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
0
10
0
0
10
0
60
20
% N
% Pro:
0
60
20
0
0
0
10
0
0
0
0
60
20
0
0
% P
% Gln:
60
20
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
10
60
20
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% S
% Thr:
10
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
60
20
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _