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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SH3GL3
All Species:
36.97
Human Site:
Y57
Identified Species:
90.37
UniProt:
Q99963
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99963
NP_003018.3
347
39285
Y57
I
L
S
K
T
T
E
Y
L
Q
P
N
P
A
Y
Chimpanzee
Pan troglodytes
XP_001161355
439
48937
Y149
I
L
S
K
T
T
E
Y
L
Q
P
N
P
A
Y
Rhesus Macaque
Macaca mulatta
XP_001111376
487
54209
Y197
I
L
S
K
T
T
E
Y
L
Q
P
N
P
A
Y
Dog
Lupus familis
XP_852298
429
47944
Y139
I
L
S
K
A
T
E
Y
L
Q
P
N
P
A
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q62421
347
38916
Y57
I
L
S
K
A
T
E
Y
L
Q
P
N
P
A
Y
Rat
Rattus norvegicus
O35180
347
39148
Y57
I
L
S
K
A
T
E
Y
L
Q
P
N
P
A
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q8AXU9
353
39987
Y57
L
L
S
K
S
T
E
Y
L
Q
P
N
P
A
Y
Frog
Xenopus laevis
NP_001088468
351
39988
Y57
L
L
S
K
T
T
E
Y
L
Q
P
N
P
A
Y
Zebra Danio
Brachydanio rerio
NP_001075160
352
39967
Y57
L
I
T
K
T
T
E
Y
L
Q
P
N
P
A
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VU84
531
58711
Y139
L
S
T
V
S
S
A
Y
S
F
K
E
P
R
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
78.8
70.4
76.2
N.A.
86.4
86.7
N.A.
N.A.
81.8
78.9
77.5
N.A.
21.4
N.A.
N.A.
N.A.
Protein Similarity:
100
78.8
70.8
78.7
N.A.
94.5
94.8
N.A.
N.A.
92.9
90
88.6
N.A.
37.6
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
86.6
93.3
73.3
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
100
100
93.3
N.A.
40
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
30
0
10
0
0
0
0
0
0
90
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
90
0
0
0
0
10
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
60
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
90
0
0
0
0
0
0
10
0
0
0
0
% K
% Leu:
40
80
0
0
0
0
0
0
90
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
90
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
90
0
100
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
90
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% R
% Ser:
0
10
80
0
20
10
0
0
10
0
0
0
0
0
10
% S
% Thr:
0
0
20
0
50
90
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
100
0
0
0
0
0
0
80
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _