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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADAM2
All Species:
16.97
Human Site:
Y47
Identified Species:
62.22
UniProt:
Q99965
Number Species:
6
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99965
NP_001455.3
735
82457
Y47
G
I
E
S
Q
A
S
Y
K
I
V
I
E
G
K
Chimpanzee
Pan troglodytes
XP_519722
735
82350
Y47
G
I
E
S
Q
A
S
Y
K
I
V
I
E
G
K
Rhesus Macaque
Macaca mulatta
XP_001095726
735
82380
Y47
E
I
E
S
Q
V
S
Y
K
I
V
I
E
G
K
Dog
Lupus familis
XP_532795
881
98895
Y151
G
L
S
Q
S
S
W
Y
H
M
K
N
E
R
C
Cat
Felis silvestris
Mouse
Mus musculus
Q60718
735
82357
Y53
G
Y
E
T
Q
V
T
Y
N
L
K
I
E
G
K
Rat
Rattus norvegicus
Q63202
737
82292
Y53
G
Y
E
T
Q
V
T
Y
S
L
K
I
E
G
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517253
692
76612
R48
F
A
G
N
R
G
T
R
A
G
Y
D
D
P
A
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.9
91.2
57.7
N.A.
60.1
60.2
N.A.
44.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.1
95.7
68.9
N.A.
76.4
76.1
N.A.
60.5
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
86.6
20
N.A.
53.3
53.3
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
86.6
40
N.A.
73.3
73.3
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
0
0
0
29
0
0
15
0
0
0
0
0
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
15
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
15
15
0
0
% D
% Glu:
15
0
72
0
0
0
0
0
0
0
0
0
86
0
0
% E
% Phe:
15
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
72
0
15
0
0
15
0
0
0
15
0
0
0
72
0
% G
% His:
0
0
0
0
0
0
0
0
15
0
0
0
0
0
0
% H
% Ile:
0
43
0
0
0
0
0
0
0
43
0
72
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
43
0
43
0
0
0
72
% K
% Leu:
0
15
0
0
0
0
0
0
0
29
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
15
0
0
0
0
0
% M
% Asn:
0
0
0
15
0
0
0
0
15
0
0
15
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
15
0
% P
% Gln:
0
0
0
15
72
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
15
0
0
15
0
0
0
0
0
15
0
% R
% Ser:
0
0
15
43
15
15
43
0
15
0
0
0
0
0
0
% S
% Thr:
0
0
0
29
0
0
43
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
43
0
0
0
0
43
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
15
0
0
0
0
0
0
0
0
% W
% Tyr:
0
29
0
0
0
0
0
86
0
0
15
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _