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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TEP1 All Species: 16.36
Human Site: S876 Identified Species: 51.43
UniProt: Q99973 Number Species: 7
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99973 NP_009041.2 2627 290490 S876 P G K T G V Q S L R P L E E D
Chimpanzee Pan troglodytes XP_001137917 2627 290911 S876 P G K T G V Q S L R P L E E D
Rhesus Macaque Macaca mulatta XP_001092046 2724 300526 S960 P G K T G V Q S L R P L E E D
Dog Lupus familis XP_539672 2603 283765 S854 P G K T G E L S L R P L E E S
Cat Felis silvestris
Mouse Mus musculus P97499 2629 291441 S885 P G K T Q A P S L R P L E E N
Rat Rattus norvegicus O08653 2629 291690 P889 P G K T K V S P L R P L E E N
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002660903 2542 286668 Q855 I P P P Q G C Q K E P E R S A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_789472 2666 295519 K941 K I Q T G K K K D L V T P E I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.4 89.6 71.3 N.A. 75.5 74.9 N.A. N.A. N.A. N.A. 31.3 N.A. N.A. N.A. N.A. 29.4
Protein Similarity: 100 99 91.8 80.2 N.A. 84.6 84.4 N.A. N.A. N.A. N.A. 49.4 N.A. N.A. N.A. N.A. 49
P-Site Identity: 100 100 100 80 N.A. 73.3 73.3 N.A. N.A. N.A. N.A. 6.6 N.A. N.A. N.A. N.A. 20
P-Site Similarity: 100 100 100 80 N.A. 80 80 N.A. N.A. N.A. N.A. 6.6 N.A. N.A. N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 13 0 0 0 0 0 0 0 0 13 % A
% Cys: 0 0 0 0 0 0 13 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 13 0 0 0 0 0 38 % D
% Glu: 0 0 0 0 0 13 0 0 0 13 0 13 75 88 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 75 0 0 63 13 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 13 13 0 0 0 0 0 0 0 0 0 0 0 0 13 % I
% Lys: 13 0 75 0 13 13 13 13 13 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 13 0 75 13 0 75 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 25 % N
% Pro: 75 13 13 13 0 0 13 13 0 0 88 0 13 0 0 % P
% Gln: 0 0 13 0 25 0 38 13 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 75 0 0 13 0 0 % R
% Ser: 0 0 0 0 0 0 13 63 0 0 0 0 0 13 13 % S
% Thr: 0 0 0 88 0 0 0 0 0 0 0 13 0 0 0 % T
% Val: 0 0 0 0 0 50 0 0 0 0 13 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _