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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VRK1
All Species:
21.82
Human Site:
T312
Identified Species:
40
UniProt:
Q99986
Number Species:
12
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99986
NP_003375.1
396
45476
T312
T
V
K
L
L
D
Y
T
E
K
P
L
Y
E
N
Chimpanzee
Pan troglodytes
XP_510157
396
45456
T312
T
V
K
L
L
D
Y
T
E
K
P
L
Y
E
N
Rhesus Macaque
Macaca mulatta
XP_001102618
396
45467
T312
T
V
K
L
L
D
Y
T
E
K
P
L
Y
Q
N
Dog
Lupus familis
XP_547970
395
44398
A312
T
V
K
L
L
G
Y
A
E
K
P
L
Y
Q
N
Cat
Felis silvestris
Mouse
Mus musculus
Q80X41
440
49722
T312
S
V
K
L
L
E
Y
T
E
K
P
L
Y
Q
N
Rat
Rattus norvegicus
P97633
325
37477
T243
I
S
E
K
K
M
S
T
P
V
E
V
L
C
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512207
479
54436
T311
T
V
K
L
L
G
Y
T
E
K
P
L
Y
Q
R
Chicken
Gallus gallus
NP_001006485
413
46937
E311
K
V
K
Q
L
G
Y
E
E
K
P
V
Y
P
H
Frog
Xenopus laevis
NP_001080108
438
49973
D301
E
I
C
H
L
A
Y
D
A
K
P
D
Y
G
A
Zebra Danio
Brachydanio rerio
Q7ZUS1
425
47752
T313
E
V
K
V
L
G
Y
T
D
R
P
D
Y
D
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KRY6
599
65975
N316
Y
V
S
K
L
T
H
N
Q
E
P
D
Y
D
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783182
473
53072
D306
H
A
F
K
L
K
Y
D
E
E
P
D
Y
N
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P23292
546
62061
E330
I
V
R
N
L
S
F
E
E
T
P
D
Y
E
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98.2
83.8
N.A.
76.8
29
N.A.
66.1
70.2
47.2
59.2
N.A.
31
N.A.
N.A.
39.7
Protein Similarity:
100
99.7
98.9
88.1
N.A.
83.4
46.4
N.A.
73
81.5
59.3
72.4
N.A.
43.7
N.A.
N.A.
56
P-Site Identity:
100
100
93.3
80
N.A.
80
6.6
N.A.
80
53.3
33.3
46.6
N.A.
26.6
N.A.
N.A.
33.3
P-Site Similarity:
100
100
100
86.6
N.A.
100
20
N.A.
86.6
66.6
40
73.3
N.A.
53.3
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
37.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
8
0
8
8
0
0
0
0
0
8
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
0
0
0
0
24
0
16
8
0
0
39
0
16
0
% D
% Glu:
16
0
8
0
0
8
0
16
70
16
8
0
0
24
0
% E
% Phe:
0
0
8
0
0
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
31
0
0
0
0
0
0
0
8
8
% G
% His:
8
0
0
8
0
0
8
0
0
0
0
0
0
0
8
% H
% Ile:
16
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
8
0
62
24
8
8
0
0
0
62
0
0
0
0
31
% K
% Leu:
0
0
0
47
93
0
0
0
0
0
0
47
8
0
0
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
0
8
0
0
0
0
0
8
39
% N
% Pro:
0
0
0
0
0
0
0
0
8
0
93
0
0
8
0
% P
% Gln:
0
0
0
8
0
0
0
0
8
0
0
0
0
31
0
% Q
% Arg:
0
0
8
0
0
0
0
0
0
8
0
0
0
0
8
% R
% Ser:
8
8
8
0
0
8
8
0
0
0
0
0
0
0
0
% S
% Thr:
39
0
0
0
0
8
0
54
0
8
0
0
0
0
0
% T
% Val:
0
77
0
8
0
0
0
0
0
8
0
16
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
77
0
0
0
0
0
93
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _