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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VRK1
All Species:
19.09
Human Site:
T355
Identified Species:
35
UniProt:
Q99986
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99986
NP_003375.1
396
45476
T355
G
L
K
A
K
T
I
T
K
K
R
K
K
E
I
Chimpanzee
Pan troglodytes
XP_510157
396
45456
T355
G
L
K
A
K
T
I
T
K
K
R
K
K
E
I
Rhesus Macaque
Macaca mulatta
XP_001102618
396
45467
T355
G
L
K
A
K
T
I
T
K
K
R
K
K
E
M
Dog
Lupus familis
XP_547970
395
44398
T355
G
L
R
A
K
S
M
T
K
P
A
T
G
I
L
Cat
Felis silvestris
Mouse
Mus musculus
Q80X41
440
49722
S355
S
V
K
T
R
P
A
S
K
K
R
K
K
E
A
Rat
Rattus norvegicus
P97633
325
37477
F285
R
Q
L
F
R
I
L
F
R
T
L
N
H
Q
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512207
479
54436
P354
D
T
R
A
K
P
G
P
K
E
M
L
F
E
L
Chicken
Gallus gallus
NP_001006485
413
46937
Q354
D
V
Q
T
N
P
V
Q
K
K
K
R
K
A
A
Frog
Xenopus laevis
NP_001080108
438
49973
G393
L
G
K
K
E
E
R
G
K
K
R
R
E
K
K
Zebra Danio
Brachydanio rerio
Q7ZUS1
425
47752
T356
T
S
L
P
S
V
K
T
P
K
R
K
K
A
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KRY6
599
65975
T367
P
G
T
S
K
A
A
T
A
R
K
A
K
K
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783182
473
53072
E361
K
R
K
A
T
S
K
E
R
E
P
A
P
K
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P23292
546
62061
A445
Q
A
Q
A
Q
Q
Q
A
N
R
Y
Q
L
Q
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98.2
83.8
N.A.
76.8
29
N.A.
66.1
70.2
47.2
59.2
N.A.
31
N.A.
N.A.
39.7
Protein Similarity:
100
99.7
98.9
88.1
N.A.
83.4
46.4
N.A.
73
81.5
59.3
72.4
N.A.
43.7
N.A.
N.A.
56
P-Site Identity:
100
100
93.3
40
N.A.
46.6
0
N.A.
26.6
20
26.6
33.3
N.A.
26.6
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
66.6
N.A.
66.6
26.6
N.A.
46.6
53.3
53.3
33.3
N.A.
53.3
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
37.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
54
0
8
16
8
8
0
8
16
0
16
16
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
16
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
8
8
0
8
0
16
0
0
8
39
8
% E
% Phe:
0
0
0
8
0
0
0
8
0
0
0
0
8
0
0
% F
% Gly:
31
16
0
0
0
0
8
8
0
0
0
0
8
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
0
0
0
0
0
8
24
0
0
0
0
0
0
8
24
% I
% Lys:
8
0
47
8
47
0
16
0
62
54
16
39
54
24
8
% K
% Leu:
8
31
16
0
0
0
8
0
0
0
8
8
8
0
16
% L
% Met:
0
0
0
0
0
0
8
0
0
0
8
0
0
0
8
% M
% Asn:
0
0
0
0
8
0
0
0
8
0
0
8
0
0
0
% N
% Pro:
8
0
0
8
0
24
0
8
8
8
8
0
8
0
8
% P
% Gln:
8
8
16
0
8
8
8
8
0
0
0
8
0
16
0
% Q
% Arg:
8
8
16
0
16
0
8
0
16
16
47
16
0
0
0
% R
% Ser:
8
8
0
8
8
16
0
8
0
0
0
0
0
0
0
% S
% Thr:
8
8
8
16
8
24
0
47
0
8
0
8
0
0
0
% T
% Val:
0
16
0
0
0
8
8
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _