KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VRK1
All Species:
30.61
Human Site:
Y194
Identified Species:
56.11
UniProt:
Q99986
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99986
NP_003375.1
396
45476
Y194
Y
K
N
P
D
Q
V
Y
L
V
D
Y
G
L
A
Chimpanzee
Pan troglodytes
XP_510157
396
45456
Y194
Y
K
N
P
D
Q
V
Y
L
V
D
Y
G
L
A
Rhesus Macaque
Macaca mulatta
XP_001102618
396
45467
Y194
Y
K
N
P
D
Q
V
Y
L
V
D
Y
G
L
A
Dog
Lupus familis
XP_547970
395
44398
Y194
Y
K
N
P
D
Q
V
Y
L
V
D
Y
G
L
A
Cat
Felis silvestris
Mouse
Mus musculus
Q80X41
440
49722
Y194
H
K
N
P
D
Q
V
Y
L
V
D
Y
G
L
A
Rat
Rattus norvegicus
P97633
325
37477
H128
I
S
R
I
E
Y
V
H
T
K
N
F
I
H
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512207
479
54436
Y193
Y
K
N
P
D
Q
V
Y
L
V
D
Y
G
L
A
Chicken
Gallus gallus
NP_001006485
413
46937
Y193
Y
K
N
P
N
Q
V
Y
L
V
D
Y
G
L
A
Frog
Xenopus laevis
NP_001080108
438
49973
Y183
Y
T
N
Q
T
E
V
Y
L
A
D
Y
G
L
S
Zebra Danio
Brachydanio rerio
Q7ZUS1
425
47752
F195
Y
T
N
P
N
Q
V
F
L
V
D
Y
G
L
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KRY6
599
65975
Q200
L
E
K
G
G
A
A
Q
A
Y
L
V
D
F
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783182
473
53072
K187
F
S
P
K
D
K
N
K
V
F
L
A
D
Y
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P23292
546
62061
H215
Q
P
D
A
N
K
V
H
L
I
D
F
G
M
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98.2
83.8
N.A.
76.8
29
N.A.
66.1
70.2
47.2
59.2
N.A.
31
N.A.
N.A.
39.7
Protein Similarity:
100
99.7
98.9
88.1
N.A.
83.4
46.4
N.A.
73
81.5
59.3
72.4
N.A.
43.7
N.A.
N.A.
56
P-Site Identity:
100
100
100
100
N.A.
93.3
6.6
N.A.
100
93.3
60
80
N.A.
0
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
33.3
N.A.
100
100
73.3
93.3
N.A.
6.6
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
37.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
8
8
0
8
8
0
8
0
0
70
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
54
0
0
0
0
0
77
0
16
0
0
% D
% Glu:
0
8
0
0
8
8
0
0
0
0
0
0
0
0
0
% E
% Phe:
8
0
0
0
0
0
0
8
0
8
0
16
0
8
0
% F
% Gly:
0
0
0
8
8
0
0
0
0
0
0
0
77
0
16
% G
% His:
8
0
0
0
0
0
0
16
0
0
0
0
0
8
0
% H
% Ile:
8
0
0
8
0
0
0
0
0
8
0
0
8
0
0
% I
% Lys:
0
54
8
8
0
16
0
8
0
8
0
0
0
0
0
% K
% Leu:
8
0
0
0
0
0
0
0
77
0
16
0
0
70
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
0
70
0
24
0
8
0
0
0
8
0
0
0
0
% N
% Pro:
0
8
8
62
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
0
0
8
0
62
0
8
0
0
0
0
0
0
0
% Q
% Arg:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
8
% R
% Ser:
0
16
0
0
0
0
0
0
0
0
0
0
0
0
8
% S
% Thr:
0
16
0
0
8
0
0
0
8
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
85
0
8
62
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
62
0
0
0
0
8
0
62
0
8
0
70
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _