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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: VRK1 All Species: 33.94
Human Site: Y311 Identified Species: 62.22
UniProt: Q99986 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99986 NP_003375.1 396 45476 Y311 E T V K L L D Y T E K P L Y E
Chimpanzee Pan troglodytes XP_510157 396 45456 Y311 E T V K L L D Y T E K P L Y E
Rhesus Macaque Macaca mulatta XP_001102618 396 45467 Y311 E T V K L L D Y T E K P L Y Q
Dog Lupus familis XP_547970 395 44398 Y311 E T V K L L G Y A E K P L Y Q
Cat Felis silvestris
Mouse Mus musculus Q80X41 440 49722 Y311 E S V K L L E Y T E K P L Y Q
Rat Rattus norvegicus P97633 325 37477 S242 K I S E K K M S T P V E V L C
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512207 479 54436 Y310 E T V K L L G Y T E K P L Y Q
Chicken Gallus gallus NP_001006485 413 46937 Y310 E K V K Q L G Y E E K P V Y P
Frog Xenopus laevis NP_001080108 438 49973 Y300 K E I C H L A Y D A K P D Y G
Zebra Danio Brachydanio rerio Q7ZUS1 425 47752 Y312 Q E V K V L G Y T D R P D Y D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7KRY6 599 65975 H315 K Y V S K L T H N Q E P D Y D
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783182 473 53072 Y305 D H A F K L K Y D E E P D Y N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P23292 546 62061 F329 E I V R N L S F E E T P D Y E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 98.2 83.8 N.A. 76.8 29 N.A. 66.1 70.2 47.2 59.2 N.A. 31 N.A. N.A. 39.7
Protein Similarity: 100 99.7 98.9 88.1 N.A. 83.4 46.4 N.A. 73 81.5 59.3 72.4 N.A. 43.7 N.A. N.A. 56
P-Site Identity: 100 100 93.3 80 N.A. 80 6.6 N.A. 86.6 60 33.3 46.6 N.A. 26.6 N.A. N.A. 33.3
P-Site Similarity: 100 100 100 86.6 N.A. 100 26.6 N.A. 93.3 66.6 46.6 80 N.A. 60 N.A. N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.8 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 37.3 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 46.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 60 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 0 0 8 0 8 8 0 0 0 0 0 % A
% Cys: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 8 % C
% Asp: 8 0 0 0 0 0 24 0 16 8 0 0 39 0 16 % D
% Glu: 62 16 0 8 0 0 8 0 16 70 16 8 0 0 24 % E
% Phe: 0 0 0 8 0 0 0 8 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 31 0 0 0 0 0 0 0 8 % G
% His: 0 8 0 0 8 0 0 8 0 0 0 0 0 0 0 % H
% Ile: 0 16 8 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 24 8 0 62 24 8 8 0 0 0 62 0 0 0 0 % K
% Leu: 0 0 0 0 47 93 0 0 0 0 0 0 47 8 0 % L
% Met: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 8 0 0 0 8 0 0 0 0 0 8 % N
% Pro: 0 0 0 0 0 0 0 0 0 8 0 93 0 0 8 % P
% Gln: 8 0 0 0 8 0 0 0 0 8 0 0 0 0 31 % Q
% Arg: 0 0 0 8 0 0 0 0 0 0 8 0 0 0 0 % R
% Ser: 0 8 8 8 0 0 8 8 0 0 0 0 0 0 0 % S
% Thr: 0 39 0 0 0 0 8 0 54 0 8 0 0 0 0 % T
% Val: 0 0 77 0 8 0 0 0 0 0 8 0 16 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 0 0 0 77 0 0 0 0 0 93 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _