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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHRS9
All Species:
31.52
Human Site:
Y238
Identified Species:
69.33
UniProt:
Q9BPW9
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BPW9
NP_001135742.1
319
35227
Y238
S
P
D
I
K
Q
Q
Y
G
E
G
Y
I
E
K
Chimpanzee
Pan troglodytes
XP_525959
319
35155
Y238
S
P
D
I
K
Q
Q
Y
G
E
G
Y
I
E
K
Rhesus Macaque
Macaca mulatta
XP_001103665
319
35154
Y238
S
P
D
I
K
Q
Q
Y
G
E
G
Y
I
E
K
Dog
Lupus familis
XP_545513
753
83853
Y672
S
P
D
I
K
Q
Q
Y
G
E
S
Y
I
E
K
Cat
Felis silvestris
Mouse
Mus musculus
Q58NB6
319
35224
Y238
S
P
D
I
K
Q
Q
Y
G
E
G
Y
I
E
K
Rat
Rattus norvegicus
Q8VD48
319
35195
Y238
S
P
D
I
K
Q
Q
Y
G
E
G
Y
I
E
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513908
344
38027
Y263
P
P
D
I
K
Q
Q
Y
G
E
G
Y
I
E
K
Chicken
Gallus gallus
Q5ZJZ5
339
38218
Y268
P
E
I
V
R
K
D
Y
G
R
K
Y
F
D
E
Frog
Xenopus laevis
Q0IH28
323
35135
E254
T
A
D
G
R
T
P
E
E
V
A
Q
T
V
L
Zebra Danio
Brachydanio rerio
Q566S6
309
33329
T235
N
M
S
I
N
A
V
T
G
D
G
S
K
Y
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9Y140
326
35725
T249
Q
L
S
L
N
A
L
T
G
S
G
S
S
Y
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
97.8
38.3
N.A.
85.8
85.5
N.A.
71.8
31.2
23.2
24.7
N.A.
25.4
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
98.1
40.1
N.A.
90.9
90.9
N.A.
80.5
51
43
43.5
N.A.
45
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
100
100
N.A.
93.3
20
6.6
20
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
93.3
53.3
20
33.3
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
19
0
0
0
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
73
0
0
0
10
0
0
10
0
0
0
10
0
% D
% Glu:
0
10
0
0
0
0
0
10
10
64
0
0
0
64
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% F
% Gly:
0
0
0
10
0
0
0
0
91
0
73
0
0
0
19
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
73
0
0
0
0
0
0
0
0
64
0
0
% I
% Lys:
0
0
0
0
64
10
0
0
0
0
10
0
10
0
64
% K
% Leu:
0
10
0
10
0
0
10
0
0
0
0
0
0
0
10
% L
% Met:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
19
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
19
64
0
0
0
0
10
0
0
0
0
0
0
0
0
% P
% Gln:
10
0
0
0
0
64
64
0
0
0
0
10
0
0
0
% Q
% Arg:
0
0
0
0
19
0
0
0
0
10
0
0
0
0
0
% R
% Ser:
55
0
19
0
0
0
0
0
0
10
10
19
10
0
0
% S
% Thr:
10
0
0
0
0
10
0
19
0
0
0
0
10
0
0
% T
% Val:
0
0
0
10
0
0
10
0
0
10
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
73
0
0
0
73
0
19
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _