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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSD17B14
All Species:
11.52
Human Site:
S74
Identified Species:
31.67
UniProt:
Q9BPX1
Number Species:
8
Phosphosite Substitution
Charge Score:
0.38
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BPX1
NP_057330.2
270
28317
S74
D
D
V
K
T
L
V
S
E
T
I
R
R
F
G
Chimpanzee
Pan troglodytes
XP_001155640
266
28437
S70
A
T
H
K
T
L
V
S
E
T
I
R
R
F
G
Rhesus Macaque
Macaca mulatta
XP_001112238
641
70289
E400
E
Q
L
E
A
A
L
E
L
T
R
Q
Q
L
G
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
NP_079606
273
28560
S74
R
D
L
Q
T
L
V
S
E
T
L
S
R
F
G
Rat
Rattus norvegicus
XP_001076540
270
28139
S74
G
D
L
Q
T
L
I
S
E
T
V
S
R
F
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001128543
277
30093
E84
E
D
I
K
K
L
I
E
I
T
V
M
T
Y
G
Zebra Danio
Brachydanio rerio
NP_001003521
271
29072
N81
E
D
I
K
Q
L
I
N
V
T
V
E
S
F
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P50160
336
35186
D121
D
D
V
R
R
A
V
D
W
A
L
S
R
H
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9MA93
289
31433
I100
E
A
K
E
P
I
M
I
A
T
D
L
G
F
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
75.9
29.3
N.A.
N.A.
80.5
80.3
N.A.
N.A.
N.A.
55.5
57.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
79.2
35.2
N.A.
N.A.
88.2
87.7
N.A.
N.A.
N.A.
71.8
73.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
80
13.3
N.A.
N.A.
66.6
60
N.A.
N.A.
N.A.
33.3
40
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
80
53.3
N.A.
N.A.
86.6
86.6
N.A.
N.A.
N.A.
66.6
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
27.3
N.A.
30.8
N.A.
N.A.
Protein Similarity:
N.A.
38.3
N.A.
47
N.A.
N.A.
P-Site Identity:
N.A.
40
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
53.3
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
12
0
0
12
23
0
0
12
12
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
23
67
0
0
0
0
0
12
0
0
12
0
0
0
0
% D
% Glu:
45
0
0
23
0
0
0
23
45
0
0
12
0
0
12
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
67
0
% F
% Gly:
12
0
0
0
0
0
0
0
0
0
0
0
12
0
89
% G
% His:
0
0
12
0
0
0
0
0
0
0
0
0
0
12
0
% H
% Ile:
0
0
23
0
0
12
34
12
12
0
23
0
0
0
0
% I
% Lys:
0
0
12
45
12
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
34
0
0
67
12
0
12
0
23
12
0
12
0
% L
% Met:
0
0
0
0
0
0
12
0
0
0
0
12
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
12
0
23
12
0
0
0
0
0
0
12
12
0
0
% Q
% Arg:
12
0
0
12
12
0
0
0
0
0
12
23
56
0
0
% R
% Ser:
0
0
0
0
0
0
0
45
0
0
0
34
12
0
0
% S
% Thr:
0
12
0
0
45
0
0
0
0
89
0
0
12
0
0
% T
% Val:
0
0
23
0
0
0
45
0
12
0
34
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _