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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C7orf25
All Species:
43.03
Human Site:
T277
Identified Species:
63.11
UniProt:
Q9BPX7
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BPX7
NP_001093328.1
421
46451
T277
I
F
K
E
K
V
L
T
E
Q
A
E
Q
E
R
Chimpanzee
Pan troglodytes
XP_519547
479
52523
T335
I
F
K
E
K
V
L
T
E
Q
A
E
Q
E
R
Rhesus Macaque
Macaca mulatta
XP_001097049
421
46517
T277
I
F
K
E
K
V
L
T
E
Q
A
E
Q
E
R
Dog
Lupus familis
XP_540362
421
46451
T277
I
F
K
E
K
V
L
T
E
Q
A
E
Q
E
R
Cat
Felis silvestris
Mouse
Mus musculus
Q91WD4
421
46523
T277
V
F
K
E
K
V
L
T
E
Q
A
E
Q
E
R
Rat
Rattus norvegicus
Q5M888
421
46446
T277
I
F
K
E
K
V
L
T
E
Q
A
E
Q
E
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506569
421
45787
T277
V
F
R
E
K
V
L
T
E
Q
A
A
Q
E
R
Chicken
Gallus gallus
XP_418867
421
46470
T277
L
F
K
E
K
V
L
T
E
Q
A
A
Q
E
R
Frog
Xenopus laevis
Q08AW5
424
46184
T280
L
F
K
E
K
V
L
T
E
Q
A
A
Q
E
R
Zebra Danio
Brachydanio rerio
Q803H0
427
47736
T293
T
F
K
E
V
V
L
T
E
Q
A
A
Q
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_612060
371
42010
R242
T
E
Q
A
E
R
E
R
A
S
P
L
K
P
L
Honey Bee
Apis mellifera
XP_394035
404
45683
T266
I
Y
R
E
P
L
L
T
Q
Q
A
E
M
E
R
Nematode Worm
Caenorhab. elegans
NP_494927
403
46276
N266
Q
F
K
E
E
M
I
N
K
H
V
E
C
E
R
Sea Urchin
Strong. purpuratus
XP_001196667
406
44608
R271
L
S
Q
Q
E
R
Q
R
P
L
L
P
E
V
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001143775
428
46785
E289
L
M
A
A
P
E
A
E
T
R
A
R
F
K
C
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_565063
434
47323
I294
R
L
V
D
M
P
E
I
E
L
E
E
K
F
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.6
99
98.5
N.A.
92.6
91.9
N.A.
86.2
80.5
78.5
72.1
N.A.
33
38.2
28
28.5
Protein Similarity:
100
87.6
99.5
100
N.A.
96.6
96.4
N.A.
91.9
90.7
89.3
82.4
N.A.
52
58.1
47.2
50.3
P-Site Identity:
100
100
100
100
N.A.
93.3
100
N.A.
80
86.6
86.6
80
N.A.
0
60
40
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
93.3
93.3
93.3
80
N.A.
20
86.6
66.6
33.3
Percent
Protein Identity:
N.A.
22.2
N.A.
20.9
N.A.
N.A.
Protein Similarity:
N.A.
40.1
N.A.
38.9
N.A.
N.A.
P-Site Identity:
N.A.
6.6
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
26.6
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
13
0
0
7
0
7
0
75
25
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
7
% C
% Asp:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
7
0
75
19
7
13
7
69
0
7
57
7
75
7
% E
% Phe:
0
69
0
0
0
0
0
0
0
0
0
0
7
7
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% H
% Ile:
38
0
0
0
0
0
7
7
0
0
0
0
0
0
0
% I
% Lys:
0
0
63
0
57
0
0
0
7
0
0
0
13
7
7
% K
% Leu:
25
7
0
0
0
7
69
0
0
13
7
7
0
0
7
% L
% Met:
0
7
0
0
7
7
0
0
0
0
0
0
7
0
0
% M
% Asn:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
13
7
0
0
7
0
7
7
0
7
0
% P
% Gln:
7
0
13
7
0
0
7
0
7
69
0
0
63
0
0
% Q
% Arg:
7
0
13
0
0
13
0
13
0
7
0
7
0
0
75
% R
% Ser:
0
7
0
0
0
0
0
0
0
7
0
0
0
0
0
% S
% Thr:
13
0
0
0
0
0
0
69
7
0
0
0
0
0
0
% T
% Val:
13
0
7
0
7
63
0
0
0
0
7
0
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _