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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZFYVE21
All Species:
18.48
Human Site:
T135
Identified Species:
58.1
UniProt:
Q9BQ24
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BQ24
NP_076976.1
234
26506
T135
G
N
S
E
K
P
E
T
M
T
C
R
L
S
N
Chimpanzee
Pan troglodytes
XP_510190
271
30071
T154
G
N
S
E
K
P
E
T
M
T
C
R
L
S
N
Rhesus Macaque
Macaca mulatta
XP_001088673
226
25474
T109
G
N
S
E
K
P
E
T
M
I
C
R
L
S
N
Dog
Lupus familis
XP_868684
234
26172
T135
G
N
S
E
K
P
E
T
M
V
C
R
L
S
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCM3
234
26029
T135
G
D
S
E
K
P
E
T
M
V
C
R
L
S
N
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515323
114
12512
N22
V
M
V
C
R
L
S
N
N
Q
R
S
L
F
L
Chicken
Gallus gallus
XP_421391
250
28394
L133
G
T
S
D
K
S
E
L
M
V
C
R
L
S
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001199278
240
27643
S129
L
E
E
G
Q
T
N
S
Y
C
K
L
T
S
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
75.2
81.1
88.4
N.A.
84.6
N.A.
N.A.
32.9
71.1
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
40.8
Protein Similarity:
100
76.7
83.3
89.7
N.A.
88.8
N.A.
N.A.
38.8
78.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
58.7
P-Site Identity:
100
100
93.3
93.3
N.A.
86.6
N.A.
N.A.
6.6
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
93.3
93.3
N.A.
93.3
N.A.
N.A.
13.3
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
13
0
0
0
0
0
13
75
0
0
0
0
% C
% Asp:
0
13
0
13
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
13
13
63
0
0
75
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
13
0
% F
% Gly:
75
0
0
13
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
13
0
0
0
0
0
% I
% Lys:
0
0
0
0
75
0
0
0
0
0
13
0
0
0
0
% K
% Leu:
13
0
0
0
0
13
0
13
0
0
0
13
88
0
13
% L
% Met:
0
13
0
0
0
0
0
0
75
0
0
0
0
0
0
% M
% Asn:
0
50
0
0
0
0
13
13
13
0
0
0
0
0
88
% N
% Pro:
0
0
0
0
0
63
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
13
0
0
0
0
13
0
0
0
0
0
% Q
% Arg:
0
0
0
0
13
0
0
0
0
0
13
75
0
0
0
% R
% Ser:
0
0
75
0
0
13
13
13
0
0
0
13
0
88
0
% S
% Thr:
0
13
0
0
0
13
0
63
0
25
0
0
13
0
0
% T
% Val:
13
0
13
0
0
0
0
0
0
38
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
13
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _