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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZFYVE21
All Species:
10.91
Human Site:
T182
Identified Species:
34.29
UniProt:
Q9BQ24
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BQ24
NP_076976.1
234
26506
T182
G
G
G
N
A
R
A
T
G
M
F
L
Q
Y
T
Chimpanzee
Pan troglodytes
XP_510190
271
30071
Y201
G
E
K
D
I
H
A
Y
T
S
L
R
G
S
Q
Rhesus Macaque
Macaca mulatta
XP_001088673
226
25474
Y156
G
E
K
D
I
H
A
Y
T
S
L
L
G
S
Q
Dog
Lupus familis
XP_868684
234
26172
T182
G
G
G
N
A
R
A
T
G
M
S
L
Q
Y
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCM3
234
26029
T182
G
A
G
S
T
R
A
T
G
M
L
L
Q
Y
T
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515323
114
12512
K69
S
G
M
L
L
Q
Y
K
A
P
G
A
E
G
M
Chicken
Gallus gallus
XP_421391
250
28394
Y180
G
E
K
D
I
H
T
Y
T
S
L
L
E
S
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001199278
240
27643
E176
N
L
Q
M
M
T
S
E
A
N
V
N
G
H
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
75.2
81.1
88.4
N.A.
84.6
N.A.
N.A.
32.9
71.1
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
40.8
Protein Similarity:
100
76.7
83.3
89.7
N.A.
88.8
N.A.
N.A.
38.8
78.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
58.7
P-Site Identity:
100
13.3
20
86.6
N.A.
73.3
N.A.
N.A.
6.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
20
26.6
86.6
N.A.
80
N.A.
N.A.
20
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
13
0
0
25
0
63
0
25
0
0
13
0
0
13
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
38
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
38
0
0
0
0
0
13
0
0
0
0
25
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
13
0
0
0
0
% F
% Gly:
75
38
38
0
0
0
0
0
38
0
13
0
38
13
0
% G
% His:
0
0
0
0
0
38
0
0
0
0
0
0
0
13
0
% H
% Ile:
0
0
0
0
38
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
38
0
0
0
0
13
0
0
0
0
0
0
0
% K
% Leu:
0
13
0
13
13
0
0
0
0
0
50
63
0
0
0
% L
% Met:
0
0
13
13
13
0
0
0
0
38
0
0
0
0
13
% M
% Asn:
13
0
0
25
0
0
0
0
0
13
0
13
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
13
0
0
0
0
0
% P
% Gln:
0
0
13
0
0
13
0
0
0
0
0
0
38
0
38
% Q
% Arg:
0
0
0
0
0
38
0
0
0
0
0
13
0
0
0
% R
% Ser:
13
0
0
13
0
0
13
0
0
38
13
0
0
38
0
% S
% Thr:
0
0
0
0
13
13
13
38
38
0
0
0
0
0
25
% T
% Val:
0
0
0
0
0
0
0
0
0
0
13
0
0
0
13
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
13
38
0
0
0
0
0
38
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _