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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX50
All Species:
24.55
Human Site:
S425
Identified Species:
49.09
UniProt:
Q9BQ39
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BQ39
NP_076950.1
737
82565
S425
L
H
G
D
I
A
Q
S
Q
R
E
I
T
L
K
Chimpanzee
Pan troglodytes
XP_507824
737
82561
S425
L
H
G
D
I
A
Q
S
Q
R
E
I
T
L
K
Rhesus Macaque
Macaca mulatta
XP_001111043
737
82547
S425
L
H
G
D
I
A
Q
S
Q
R
E
I
T
L
K
Dog
Lupus familis
XP_850174
738
82595
S426
L
H
G
D
I
A
Q
S
Q
R
E
I
T
L
K
Cat
Felis silvestris
Mouse
Mus musculus
Q99MJ9
734
82157
S422
L
H
G
D
I
A
Q
S
Q
R
E
I
T
L
K
Rat
Rattus norvegicus
Q3B8Q1
782
85947
K470
L
H
G
D
I
P
Q
K
Q
R
E
I
T
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519332
790
87754
S470
L
H
G
D
I
A
Q
S
Q
R
E
I
T
L
K
Chicken
Gallus gallus
XP_001232052
713
79167
L414
I
K
Q
D
C
Q
S
L
H
G
D
I
P
Q
K
Frog
Xenopus laevis
NP_001082033
800
89347
S499
N
C
G
S
L
K
Q
S
A
K
P
L
H
G
D
Zebra Danio
Brachydanio rerio
NP_001120807
759
84566
K454
L
H
G
D
I
P
Q
K
Q
R
E
V
T
L
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786504
657
72975
V358
G
L
D
G
R
C
M
V
F
C
E
T
K
R
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39189
671
72872
G372
E
L
S
G
L
L
D
G
S
R
A
L
H
G
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.7
97.8
N.A.
95.5
56
N.A.
60.7
59.8
48.6
56.6
N.A.
N.A.
N.A.
N.A.
44.6
Protein Similarity:
100
100
100
99.1
N.A.
97.6
69.6
N.A.
73.8
72.8
65.7
70.4
N.A.
N.A.
N.A.
N.A.
62.1
P-Site Identity:
100
100
100
100
N.A.
100
86.6
N.A.
100
20
20
80
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
86.6
N.A.
100
33.3
40
86.6
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
53.3
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
50
0
0
9
0
9
0
0
0
0
% A
% Cys:
0
9
0
0
9
9
0
0
0
9
0
0
0
0
0
% C
% Asp:
0
0
9
75
0
0
9
0
0
0
9
0
0
0
17
% D
% Glu:
9
0
0
0
0
0
0
0
0
0
75
0
0
0
9
% E
% Phe:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% F
% Gly:
9
0
75
17
0
0
0
9
0
9
0
0
0
17
0
% G
% His:
0
67
0
0
0
0
0
0
9
0
0
0
17
0
0
% H
% Ile:
9
0
0
0
67
0
0
0
0
0
0
67
0
0
0
% I
% Lys:
0
9
0
0
0
9
0
17
0
9
0
0
9
0
75
% K
% Leu:
67
17
0
0
17
9
0
9
0
0
0
17
0
67
0
% L
% Met:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
17
0
0
0
0
9
0
9
0
0
% P
% Gln:
0
0
9
0
0
9
75
0
67
0
0
0
0
9
0
% Q
% Arg:
0
0
0
0
9
0
0
0
0
75
0
0
0
9
0
% R
% Ser:
0
0
9
9
0
0
9
59
9
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
9
67
0
0
% T
% Val:
0
0
0
0
0
0
0
9
0
0
0
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _