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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GRWD1
All Species:
16.97
Human Site:
S21
Identified Species:
28.72
UniProt:
Q9BQ67
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BQ67
NP_113673.3
446
49419
S21
G
E
P
M
E
A
E
S
G
D
T
S
S
E
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001113650
446
49405
S21
G
E
P
M
E
A
E
S
G
D
T
S
P
E
G
Dog
Lupus familis
XP_854878
440
48695
S21
G
E
P
M
E
A
E
S
S
G
S
S
Q
V
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q810D6
446
49215
T21
G
E
P
M
E
A
E
T
C
D
P
G
T
E
G
Rat
Rattus norvegicus
Q5XI13
445
49150
T21
G
E
P
M
E
A
E
T
Y
D
L
G
S
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q9W7I5
425
47588
E20
E
E
R
V
I
N
E
E
Y
K
I
W
K
K
N
Frog
Xenopus laevis
O93377
425
47550
E20
E
E
R
V
I
N
E
E
Y
K
I
W
K
K
N
Zebra Danio
Brachydanio rerio
Q7ZTY4
426
47733
I22
V
I
N
E
E
Y
K
I
W
K
K
N
T
P
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24572
430
48616
I27
V
I
N
E
E
Y
K
I
W
K
K
N
T
P
F
Honey Bee
Apis mellifera
XP_001121876
431
48870
S24
S
N
D
S
D
K
D
S
T
E
N
D
E
V
Q
Nematode Worm
Caenorhab. elegans
NP_498091
453
50593
E31
E
V
D
E
T
D
D
E
D
E
E
V
P
E
N
Sea Urchin
Strong. purpuratus
XP_786328
581
65430
G41
E
D
H
E
D
G
E
G
S
S
E
S
Q
R
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001136925
481
52996
S26
K
T
E
S
S
S
S
S
N
P
A
I
A
S
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q04225
511
57243
Q85
E
T
L
V
Q
K
D
Q
S
E
G
N
K
E
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.9
91.9
N.A.
91.4
92.1
N.A.
N.A.
23.3
23.5
23.3
N.A.
23
47.7
43.9
43
Protein Similarity:
100
N.A.
98.8
96.6
N.A.
97
96.8
N.A.
N.A.
40.1
40.3
39.6
N.A.
39.6
66.8
60.7
56.4
P-Site Identity:
100
N.A.
93.3
60
N.A.
66.6
73.3
N.A.
N.A.
13.3
13.3
6.6
N.A.
6.6
6.6
6.6
13.3
P-Site Similarity:
100
N.A.
93.3
66.6
N.A.
80
80
N.A.
N.A.
26.6
26.6
26.6
N.A.
26.6
26.6
20
26.6
Percent
Protein Identity:
N.A.
42.2
N.A.
N.A.
33
N.A.
Protein Similarity:
N.A.
58.4
N.A.
N.A.
50.2
N.A.
P-Site Identity:
N.A.
13.3
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
26.6
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
36
0
0
0
0
8
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
0
8
15
0
15
8
22
0
8
29
0
8
0
0
0
% D
% Glu:
36
50
8
29
50
0
58
22
0
22
15
0
8
43
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
15
% F
% Gly:
36
0
0
0
0
8
0
8
15
8
8
15
0
0
36
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
15
0
0
15
0
0
15
0
0
15
8
0
0
0
% I
% Lys:
8
0
0
0
0
15
15
0
0
29
15
0
22
15
8
% K
% Leu:
0
0
8
0
0
0
0
0
0
0
8
0
0
0
0
% L
% Met:
0
0
0
36
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
15
0
0
15
0
0
8
0
8
22
0
0
22
% N
% Pro:
0
0
36
0
0
0
0
0
0
8
8
0
15
15
0
% P
% Gln:
0
0
0
0
8
0
0
8
0
0
0
0
15
0
15
% Q
% Arg:
0
0
15
0
0
0
0
0
0
0
0
0
0
8
0
% R
% Ser:
8
0
0
15
8
8
8
36
22
8
8
29
15
8
0
% S
% Thr:
0
15
0
0
8
0
0
15
8
0
15
0
22
0
0
% T
% Val:
15
8
0
22
0
0
0
0
0
0
0
8
0
15
0
% V
% Trp:
0
0
0
0
0
0
0
0
15
0
0
15
0
0
0
% W
% Tyr:
0
0
0
0
0
15
0
0
22
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _