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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TCF25
All Species:
27.88
Human Site:
S172
Identified Species:
55.76
UniProt:
Q9BQ70
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BQ70
NP_055787.1
676
76667
S172
R
P
G
P
A
P
L
S
S
R
K
H
V
L
Y
Chimpanzee
Pan troglodytes
XP_511180
632
71641
S128
R
P
G
P
A
P
L
S
S
R
K
H
V
L
Y
Rhesus Macaque
Macaca mulatta
XP_001090795
676
76520
S172
R
P
G
P
A
P
L
S
S
R
K
H
I
L
Y
Dog
Lupus familis
XP_849916
677
76749
S173
R
P
G
P
P
P
L
S
S
K
K
H
V
L
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q8R3L2
676
76666
S172
H
P
G
P
P
P
L
S
S
R
K
H
V
L
Y
Rat
Rattus norvegicus
XP_001079503
781
88124
S277
H
P
G
P
P
P
L
S
S
R
K
H
V
L
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510966
647
74062
T146
Q
P
Q
I
G
V
I
T
E
S
R
P
L
L
Y
Chicken
Gallus gallus
XP_423211
609
70005
N106
Q
T
D
G
K
G
T
N
Q
P
D
Q
R
I
E
Frog
Xenopus laevis
NP_001091405
675
77146
T168
Q
T
I
S
S
G
S
T
E
S
R
P
L
L
Y
Zebra Danio
Brachydanio rerio
NP_001005399
650
75570
S141
Q
S
A
E
N
S
A
S
E
R
R
P
V
L
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393600
597
68971
K131
N
L
Q
W
I
E
Q
K
S
K
E
D
I
L
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001181383
722
81140
A191
F
D
Q
G
S
R
T
A
N
S
K
P
L
L
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.8
94.8
87.8
N.A.
90.3
77.9
N.A.
58.8
58.7
59.7
56.3
N.A.
N.A.
36
N.A.
40.4
Protein Similarity:
100
92
96.7
93.2
N.A.
93.7
81.1
N.A.
72.9
73
73.2
69.5
N.A.
N.A.
55.6
N.A.
57
P-Site Identity:
100
100
93.3
86.6
N.A.
86.6
86.6
N.A.
20
0
13.3
33.3
N.A.
N.A.
13.3
N.A.
13.3
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
53.3
20
46.6
46.6
N.A.
N.A.
33.3
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
25
0
9
9
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% C
% Asp:
0
9
9
0
0
0
0
0
0
0
9
9
0
0
0
% D
% Glu:
0
0
0
9
0
9
0
0
25
0
9
0
0
0
9
% E
% Phe:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
50
17
9
17
0
0
0
0
0
0
0
0
0
% G
% His:
17
0
0
0
0
0
0
0
0
0
0
50
0
0
0
% H
% Ile:
0
0
9
9
9
0
9
0
0
0
0
0
17
9
0
% I
% Lys:
0
0
0
0
9
0
0
9
0
17
59
0
0
0
0
% K
% Leu:
0
9
0
0
0
0
50
0
0
0
0
0
25
92
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
0
0
9
0
0
9
9
0
0
0
0
0
0
% N
% Pro:
0
59
0
50
25
50
0
0
0
9
0
34
0
0
0
% P
% Gln:
34
0
25
0
0
0
9
0
9
0
0
9
0
0
0
% Q
% Arg:
34
0
0
0
0
9
0
0
0
50
25
0
9
0
0
% R
% Ser:
0
9
0
9
17
9
9
59
59
25
0
0
0
0
0
% S
% Thr:
0
17
0
0
0
0
17
17
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
9
0
0
0
0
0
0
50
0
0
% V
% Trp:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
75
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _