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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TCF25 All Species: 36.06
Human Site: T189 Identified Species: 72.12
UniProt: Q9BQ70 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BQ70 NP_055787.1 676 76667 T189 H R H L N P D T E L K R Y F G
Chimpanzee Pan troglodytes XP_511180 632 71641 T145 H R H L N P D T E L K R Y F G
Rhesus Macaque Macaca mulatta XP_001090795 676 76520 T189 H R H L N P D T E L K R Y F G
Dog Lupus familis XP_849916 677 76749 T190 H R H L N P D T E L K R Y F G
Cat Felis silvestris
Mouse Mus musculus Q8R3L2 676 76666 T189 H R H L N P D T E L K R Y F G
Rat Rattus norvegicus XP_001079503 781 88124 T294 H R H L N P D T E L K R Y F G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510966 647 74062 T163 H R N L N P E T E L K R Y F G
Chicken Gallus gallus XP_423211 609 70005 L123 N L N P E N E L K R Y F G A R
Frog Xenopus laevis NP_001091405 675 77146 T185 H R N L N P E T E L K K Y F G
Zebra Danio Brachydanio rerio NP_001005399 650 75570 T158 H R N L N S E T E L K R F F G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_393600 597 68971 N148 H K H L N P Y N E L K R I F G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001181383 722 81140 N208 H K H L N P E N E L R R I F G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90.8 94.8 87.8 N.A. 90.3 77.9 N.A. 58.8 58.7 59.7 56.3 N.A. N.A. 36 N.A. 40.4
Protein Similarity: 100 92 96.7 93.2 N.A. 93.7 81.1 N.A. 72.9 73 73.2 69.5 N.A. N.A. 55.6 N.A. 57
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 86.6 0 80 73.3 N.A. N.A. 73.3 N.A. 66.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 26.6 100 93.3 N.A. N.A. 80 N.A. 86.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 50 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 9 0 42 0 92 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 9 9 92 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 92 % G
% His: 92 0 67 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 17 0 0 % I
% Lys: 0 17 0 0 0 0 0 0 9 0 84 9 0 0 0 % K
% Leu: 0 9 0 92 0 0 0 9 0 92 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 9 0 34 0 92 9 0 17 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 9 0 84 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 75 0 0 0 0 0 0 0 9 9 84 0 0 9 % R
% Ser: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 75 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 9 0 0 0 9 0 67 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _