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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TCF25
All Species:
25.76
Human Site:
T221
Identified Species:
51.52
UniProt:
Q9BQ70
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BQ70
NP_055787.1
676
76667
T221
P
K
C
T
W
L
T
T
P
K
S
T
W
P
R
Chimpanzee
Pan troglodytes
XP_511180
632
71641
T177
P
K
C
T
W
L
T
T
P
K
S
T
W
P
R
Rhesus Macaque
Macaca mulatta
XP_001090795
676
76520
T221
P
K
C
T
W
L
T
T
P
K
S
T
W
P
R
Dog
Lupus familis
XP_849916
677
76749
T222
P
K
C
T
W
L
T
T
P
K
S
T
W
P
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8R3L2
676
76666
T221
P
K
C
T
W
L
T
T
P
K
S
T
W
P
R
Rat
Rattus norvegicus
XP_001079503
781
88124
T326
P
K
C
T
W
L
T
T
P
K
S
T
W
P
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510966
647
74062
A195
H
H
S
T
W
L
T
A
P
K
D
T
W
P
R
Chicken
Gallus gallus
XP_423211
609
70005
A153
V
R
S
T
W
L
T
A
P
K
N
T
W
P
R
Frog
Xenopus laevis
NP_001091405
675
77146
A218
H
R
S
T
W
L
T
A
P
K
S
T
W
P
R
Zebra Danio
Brachydanio rerio
NP_001005399
650
75570
V190
H
R
C
T
W
M
T
V
F
K
D
T
W
P
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393600
597
68971
D185
T
W
L
V
S
A
R
D
N
W
P
P
I
N
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001181383
722
81140
T240
Q
K
S
T
W
L
V
T
A
K
Q
S
W
P
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.8
94.8
87.8
N.A.
90.3
77.9
N.A.
58.8
58.7
59.7
56.3
N.A.
N.A.
36
N.A.
40.4
Protein Similarity:
100
92
96.7
93.2
N.A.
93.7
81.1
N.A.
72.9
73
73.2
69.5
N.A.
N.A.
55.6
N.A.
57
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
66.6
66.6
73.3
60
N.A.
N.A.
0
N.A.
53.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
66.6
80
80
73.3
N.A.
N.A.
6.6
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
9
0
25
9
0
0
0
0
0
0
% A
% Cys:
0
0
59
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
9
0
0
17
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
25
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% I
% Lys:
0
59
0
0
0
0
0
0
0
92
0
0
0
0
17
% K
% Leu:
0
0
9
0
0
84
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
9
0
9
0
0
9
0
% N
% Pro:
50
0
0
0
0
0
0
0
75
0
9
9
0
92
0
% P
% Gln:
9
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% Q
% Arg:
0
25
0
0
0
0
9
0
0
0
0
0
0
0
84
% R
% Ser:
0
0
34
0
9
0
0
0
0
0
59
9
0
0
0
% S
% Thr:
9
0
0
92
0
0
84
59
0
0
0
84
0
0
0
% T
% Val:
9
0
0
9
0
0
9
9
0
0
0
0
0
0
0
% V
% Trp:
0
9
0
0
92
0
0
0
0
9
0
0
92
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _