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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GIYD1
All Species:
8.79
Human Site:
S262
Identified Species:
16.11
UniProt:
Q9BQ83
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BQ83
NP_001014999.1
275
30771
S262
T
E
K
E
V
E
D
S
E
L
E
E
A
H
W
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001109511
275
30869
S262
T
E
K
E
V
E
D
S
E
L
E
E
A
H
W
Dog
Lupus familis
XP_849594
272
30703
L259
N
E
E
E
E
E
D
L
E
L
E
E
E
H
W
Cat
Felis silvestris
Mouse
Mus musculus
Q8BX32
270
30638
E258
T
E
E
E
E
D
L
E
L
E
E
E
H
W
T
Rat
Rattus norvegicus
Q5PQP5
271
30728
L258
T
E
E
E
E
V
D
L
E
L
E
E
E
H
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517370
312
34146
E253
R
R
S
P
E
E
E
E
E
E
E
E
L
S
P
Chicken
Gallus gallus
Frog
Xenopus laevis
Q0IH86
282
32557
S267
Y
G
D
L
E
E
I
S
S
S
Q
A
H
W
G
Zebra Danio
Brachydanio rerio
XP_001337124
260
30207
I247
A
D
L
E
E
M
N
I
P
S
S
Q
N
H
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VN41
297
34073
Q273
L
G
V
P
E
E
L
Q
D
H
D
E
D
L
S
Honey Bee
Apis mellifera
XP_001121578
222
26177
I210
N
V
L
W
G
D
L
I
R
K
K
I
G
T
L
Nematode Worm
Caenorhab. elegans
P91351
443
50517
A419
I
K
I
S
T
K
C
A
E
E
F
Q
N
M
V
Sea Urchin
Strong. purpuratus
XP_783475
226
26342
S211
Y
A
K
L
A
E
I
S
E
E
D
E
S
D
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_180594
368
41382
S346
S
P
S
C
R
A
G
S
S
M
K
R
R
R
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
96.7
81.8
N.A.
76
75.2
N.A.
45.8
N.A.
52.4
48.7
N.A.
38.7
38.9
23.9
27.6
Protein Similarity:
100
N.A.
98.1
88.7
N.A.
83.2
83.2
N.A.
54.4
N.A.
68
64.7
N.A.
56.9
54.5
34.7
40.3
P-Site Identity:
100
N.A.
100
66.6
N.A.
33.3
66.6
N.A.
26.6
N.A.
13.3
20
N.A.
13.3
0
6.6
33.3
P-Site Similarity:
100
N.A.
100
73.3
N.A.
46.6
73.3
N.A.
33.3
N.A.
20
40
N.A.
26.6
13.3
33.3
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.8
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
8
8
0
8
0
0
0
8
16
0
0
% A
% Cys:
0
0
0
8
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
8
0
0
16
31
0
8
0
16
0
8
8
0
% D
% Glu:
0
39
24
47
54
54
8
16
54
31
47
62
16
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% F
% Gly:
0
16
0
0
8
0
8
0
0
0
0
0
8
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
16
39
8
% H
% Ile:
8
0
8
0
0
0
16
16
0
0
0
8
0
0
0
% I
% Lys:
0
8
24
0
0
8
0
0
0
8
16
0
0
0
0
% K
% Leu:
8
0
16
16
0
0
24
16
8
31
0
0
8
8
8
% L
% Met:
0
0
0
0
0
8
0
0
0
8
0
0
0
8
0
% M
% Asn:
16
0
0
0
0
0
8
0
0
0
0
0
16
0
0
% N
% Pro:
0
8
0
16
0
0
0
0
8
0
0
0
0
0
8
% P
% Gln:
0
0
0
0
0
0
0
8
0
0
8
16
0
0
0
% Q
% Arg:
8
8
0
0
8
0
0
0
8
0
0
8
8
8
0
% R
% Ser:
8
0
16
8
0
0
0
39
16
16
8
0
8
8
8
% S
% Thr:
31
0
0
0
8
0
0
0
0
0
0
0
0
8
8
% T
% Val:
0
8
8
0
16
8
0
0
0
0
0
0
0
0
16
% V
% Trp:
0
0
0
8
0
0
0
0
0
0
0
0
0
16
39
% W
% Tyr:
16
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _