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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLHDC3
All Species:
33.03
Human Site:
Y212
Identified Species:
66.06
UniProt:
Q9BQ90
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BQ90
NP_476502.1
382
43088
Y212
F
H
S
N
N
E
I
Y
C
N
R
I
R
V
F
Chimpanzee
Pan troglodytes
XP_518484
389
43846
Y212
F
H
S
N
N
E
I
Y
C
N
R
I
R
V
F
Rhesus Macaque
Macaca mulatta
XP_001090916
382
43096
Y212
F
H
S
N
N
E
I
Y
C
N
R
I
R
V
F
Dog
Lupus familis
XP_865234
382
43067
Y212
F
H
S
N
N
E
I
Y
C
N
R
I
R
V
F
Cat
Felis silvestris
Mouse
Mus musculus
Q8VEM9
382
43063
Y212
F
H
S
N
N
E
I
Y
C
N
R
I
R
V
F
Rat
Rattus norvegicus
Q6AYI2
382
43090
Y212
F
H
S
N
N
E
I
Y
C
N
R
I
R
V
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508538
534
60712
Y212
F
H
S
S
N
E
I
Y
C
N
R
I
R
V
F
Chicken
Gallus gallus
Q5ZJ37
371
40041
I221
F
Y
N
D
L
F
C
I
D
T
T
D
M
K
W
Frog
Xenopus laevis
Q5U580
411
46740
I258
T
A
Y
S
L
E
K
I
H
A
Y
N
F
E
T
Zebra Danio
Brachydanio rerio
NP_998434
226
25323
R77
A
R
E
V
P
Y
M
R
Y
G
H
T
A
V
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_001122948
420
47508
Y228
F
H
T
I
H
D
Q
Y
D
D
T
L
M
A
L
Sea Urchin
Strong. purpuratus
XP_001189761
385
43853
Y211
W
Y
T
G
Q
E
F
Y
C
N
E
L
K
M
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.4
99.7
97.9
N.A.
96.8
97.1
N.A.
59.9
23.2
20.6
48.6
N.A.
N.A.
N.A.
40.9
47
Protein Similarity:
100
97.6
100
98.6
N.A.
98.4
98.4
N.A.
64.6
39.2
36.7
54.4
N.A.
N.A.
N.A.
57.6
64.4
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
93.3
6.6
6.6
6.6
N.A.
N.A.
N.A.
20
33.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
33.3
13.3
13.3
N.A.
N.A.
N.A.
53.3
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
0
0
0
0
0
0
0
9
0
0
9
9
0
% A
% Cys:
0
0
0
0
0
0
9
0
67
0
0
0
0
0
0
% C
% Asp:
0
0
0
9
0
9
0
0
17
9
0
9
0
0
0
% D
% Glu:
0
0
9
0
0
75
0
0
0
0
9
0
0
9
0
% E
% Phe:
75
0
0
0
0
9
9
0
0
0
0
0
9
0
67
% F
% Gly:
0
0
0
9
0
0
0
0
0
9
0
0
0
0
0
% G
% His:
0
67
0
0
9
0
0
0
9
0
9
0
0
0
0
% H
% Ile:
0
0
0
9
0
0
59
17
0
0
0
59
0
0
0
% I
% Lys:
0
0
0
0
0
0
9
0
0
0
0
0
9
9
0
% K
% Leu:
0
0
0
0
17
0
0
0
0
0
0
17
0
0
17
% L
% Met:
0
0
0
0
0
0
9
0
0
0
0
0
17
9
0
% M
% Asn:
0
0
9
50
59
0
0
0
0
67
0
9
0
0
0
% N
% Pro:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
9
0
9
0
0
0
0
0
0
0
0
% Q
% Arg:
0
9
0
0
0
0
0
9
0
0
59
0
59
0
0
% R
% Ser:
0
0
59
17
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
9
0
17
0
0
0
0
0
0
9
17
9
0
0
9
% T
% Val:
0
0
0
9
0
0
0
0
0
0
0
0
0
67
0
% V
% Trp:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% W
% Tyr:
0
17
9
0
0
9
0
75
9
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _