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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLHDC3
All Species:
30
Human Site:
Y252
Identified Species:
60
UniProt:
Q9BQ90
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BQ90
NP_476502.1
382
43088
Y252
F
G
Y
N
G
E
L
Y
I
F
G
G
Y
N
A
Chimpanzee
Pan troglodytes
XP_518484
389
43846
Y252
F
G
Y
N
G
E
L
Y
I
F
G
G
Y
N
A
Rhesus Macaque
Macaca mulatta
XP_001090916
382
43096
Y252
F
G
Y
N
G
E
L
Y
I
F
G
G
Y
N
A
Dog
Lupus familis
XP_865234
382
43067
Y252
F
G
Y
N
G
E
L
Y
I
F
G
G
Y
N
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8VEM9
382
43063
Y252
F
G
Y
N
G
E
L
Y
I
F
G
G
Y
N
A
Rat
Rattus norvegicus
Q6AYI2
382
43090
Y252
F
G
Y
N
G
E
L
Y
I
F
G
G
Y
N
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508538
534
60712
Y252
F
G
Y
N
G
E
L
Y
I
F
G
G
Y
N
S
Chicken
Gallus gallus
Q5ZJ37
371
40041
P261
Y
I
F
G
G
I
G
P
D
G
T
L
D
T
T
Frog
Xenopus laevis
Q5U580
411
46740
F298
V
Q
I
K
N
E
V
F
I
C
G
G
Y
N
G
Zebra Danio
Brachydanio rerio
NP_998434
226
25323
T117
I
N
Q
H
R
W
F
T
P
K
I
S
G
T
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_001122948
420
47508
K268
S
T
W
V
Y
D
G
K
M
Y
M
F
G
G
Y
Sea Urchin
Strong. purpuratus
XP_001189761
385
43853
S251
V
L
Y
D
N
H
L
S
V
F
A
G
F
N
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.4
99.7
97.9
N.A.
96.8
97.1
N.A.
59.9
23.2
20.6
48.6
N.A.
N.A.
N.A.
40.9
47
Protein Similarity:
100
97.6
100
98.6
N.A.
98.4
98.4
N.A.
64.6
39.2
36.7
54.4
N.A.
N.A.
N.A.
57.6
64.4
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
93.3
6.6
40
0
N.A.
N.A.
N.A.
0
33.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
20
53.3
6.6
N.A.
N.A.
N.A.
26.6
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
50
% A
% Cys:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% C
% Asp:
0
0
0
9
0
9
0
0
9
0
0
0
9
0
0
% D
% Glu:
0
0
0
0
0
67
0
0
0
0
0
0
0
0
0
% E
% Phe:
59
0
9
0
0
0
9
9
0
67
0
9
9
0
0
% F
% Gly:
0
59
0
9
67
0
17
0
0
9
67
75
17
9
9
% G
% His:
0
0
0
9
0
9
0
0
0
0
0
0
0
0
9
% H
% Ile:
9
9
9
0
0
9
0
0
67
0
9
0
0
0
0
% I
% Lys:
0
0
0
9
0
0
0
9
0
9
0
0
0
0
0
% K
% Leu:
0
9
0
0
0
0
67
0
0
0
0
9
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
9
0
9
0
0
0
0
% M
% Asn:
0
9
0
59
17
0
0
0
0
0
0
0
0
75
0
% N
% Pro:
0
0
0
0
0
0
0
9
9
0
0
0
0
0
0
% P
% Gln:
0
9
9
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
9
0
0
0
0
0
0
9
0
0
0
9
0
0
9
% S
% Thr:
0
9
0
0
0
0
0
9
0
0
9
0
0
17
9
% T
% Val:
17
0
0
9
0
0
9
0
9
0
0
0
0
0
9
% V
% Trp:
0
0
9
0
0
9
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
67
0
9
0
0
59
0
9
0
0
67
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _