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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ECSIT
All Species:
31.82
Human Site:
S269
Identified Species:
63.64
UniProt:
Q9BQ95
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BQ95
NP_001135936.1
431
49148
S269
P
H
I
V
G
I
Q
S
P
D
Q
Q
A
A
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001106441
430
49012
S269
P
H
I
V
G
I
Q
S
P
D
Q
Q
A
A
L
Dog
Lupus familis
XP_542054
433
48862
T269
P
H
I
V
G
I
Q
T
P
D
Q
Q
A
A
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZH6
435
49780
S269
P
H
I
V
G
I
Q
S
P
D
Q
Q
A
A
L
Rat
Rattus norvegicus
Q5XIC2
434
49601
S268
P
H
I
V
G
I
Q
S
P
D
Q
Q
A
A
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520260
452
51596
S297
P
H
I
I
G
I
Q
S
P
D
Q
Q
A
A
L
Chicken
Gallus gallus
Frog
Xenopus laevis
A2VD95
410
47567
S253
L
H
I
V
G
I
Q
S
P
S
Q
V
S
L
L
Zebra Danio
Brachydanio rerio
Q08CK1
452
52168
S282
P
H
I
V
G
I
Q
S
P
D
Q
R
S
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9U6M0
409
47046
K250
G
M
S
P
E
Q
E
K
L
L
R
E
H
S
R
Honey Bee
Apis mellifera
XP_001122337
353
41789
E218
S
M
S
R
S
Q
Q
E
L
L
A
V
Q
P
T
Nematode Worm
Caenorhab. elegans
NP_500631
350
40617
K215
D
S
S
D
P
Q
Q
K
W
L
A
T
S
Q
S
Sea Urchin
Strong. purpuratus
XP_794444
398
45864
S244
E
A
E
F
T
V
Y
S
V
D
R
S
S
E
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
92.5
78.2
N.A.
73.3
72.5
N.A.
59.9
N.A.
45.7
48.4
N.A.
32.7
27.8
27.8
33.6
Protein Similarity:
100
N.A.
95.8
86.8
N.A.
82
81.5
N.A.
70.5
N.A.
63.5
63.5
N.A.
53.5
48.4
46.8
52.2
P-Site Identity:
100
N.A.
100
93.3
N.A.
100
100
N.A.
93.3
N.A.
66.6
80
N.A.
0
6.6
6.6
13.3
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
100
N.A.
73.3
93.3
N.A.
26.6
6.6
13.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
0
0
0
0
0
17
0
50
50
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
9
0
0
0
0
0
67
0
0
0
0
0
% D
% Glu:
9
0
9
0
9
0
9
9
0
0
0
9
0
9
0
% E
% Phe:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
0
0
0
67
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
67
0
0
0
0
0
0
0
0
0
0
9
0
0
% H
% Ile:
0
0
67
9
0
67
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
17
0
0
0
0
0
0
0
% K
% Leu:
9
0
0
0
0
0
0
0
17
25
0
0
0
17
67
% L
% Met:
0
17
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
59
0
0
9
9
0
0
0
67
0
0
0
0
9
0
% P
% Gln:
0
0
0
0
0
25
84
0
0
0
67
50
9
9
0
% Q
% Arg:
0
0
0
9
0
0
0
0
0
0
17
9
0
0
9
% R
% Ser:
9
9
25
0
9
0
0
67
0
9
0
9
34
9
9
% S
% Thr:
0
0
0
0
9
0
0
9
0
0
0
9
0
0
17
% T
% Val:
0
0
0
59
0
9
0
0
9
0
0
17
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _