KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ECSIT
All Species:
5.76
Human Site:
S49
Identified Species:
11.52
UniProt:
Q9BQ95
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BQ95
NP_001135936.1
431
49148
S49
H
C
S
A
A
A
H
S
S
E
Q
S
L
V
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001106441
430
49012
S49
H
C
S
A
A
P
H
S
S
E
Q
S
L
V
S
Dog
Lupus familis
XP_542054
433
48862
N49
H
R
S
A
I
A
C
N
S
D
S
W
L
V
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZH6
435
49780
K49
H
C
S
A
A
T
H
K
D
E
P
W
L
V
P
Rat
Rattus norvegicus
Q5XIC2
434
49601
D49
C
S
A
V
T
H
K
D
D
V
W
L
V
P
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520260
452
51596
T76
L
G
I
N
G
L
L
T
G
Q
V
S
F
P
I
Chicken
Gallus gallus
Frog
Xenopus laevis
A2VD95
410
47567
T49
Q
P
P
G
P
P
Q
T
T
S
S
A
G
S
V
Zebra Danio
Brachydanio rerio
Q08CK1
452
52168
F51
Y
V
Q
L
L
R
P
F
H
R
S
A
V
C
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9U6M0
409
47046
P52
K
P
G
T
K
N
L
P
A
L
R
N
P
F
A
Honey Bee
Apis mellifera
XP_001122337
353
41789
R49
H
V
Y
K
K
E
D
R
I
R
K
G
Q
L
Q
Nematode Worm
Caenorhab. elegans
NP_500631
350
40617
I51
K
D
A
F
M
A
A
I
A
T
F
K
E
K
R
Sea Urchin
Strong. purpuratus
XP_794444
398
45864
L49
F
H
T
C
A
R
C
L
R
D
S
D
I
P
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
92.5
78.2
N.A.
73.3
72.5
N.A.
59.9
N.A.
45.7
48.4
N.A.
32.7
27.8
27.8
33.6
Protein Similarity:
100
N.A.
95.8
86.8
N.A.
82
81.5
N.A.
70.5
N.A.
63.5
63.5
N.A.
53.5
48.4
46.8
52.2
P-Site Identity:
100
N.A.
86.6
53.3
N.A.
66.6
0
N.A.
6.6
N.A.
0
0
N.A.
0
6.6
6.6
6.6
P-Site Similarity:
100
N.A.
86.6
66.6
N.A.
66.6
13.3
N.A.
20
N.A.
20
20
N.A.
20
20
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
17
34
34
25
9
0
17
0
0
17
0
0
17
% A
% Cys:
9
25
0
9
0
0
17
0
0
0
0
0
0
9
0
% C
% Asp:
0
9
0
0
0
0
9
9
17
17
0
9
0
0
0
% D
% Glu:
0
0
0
0
0
9
0
0
0
25
0
0
9
0
0
% E
% Phe:
9
0
0
9
0
0
0
9
0
0
9
0
9
9
0
% F
% Gly:
0
9
9
9
9
0
0
0
9
0
0
9
9
0
0
% G
% His:
42
9
0
0
0
9
25
0
9
0
0
0
0
0
0
% H
% Ile:
0
0
9
0
9
0
0
9
9
0
0
0
9
0
9
% I
% Lys:
17
0
0
9
17
0
9
9
0
0
9
9
0
9
0
% K
% Leu:
9
0
0
9
9
9
17
9
0
9
0
9
34
9
0
% L
% Met:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
9
0
9
0
9
0
0
0
9
0
0
0
% N
% Pro:
0
17
9
0
9
17
9
9
0
0
9
0
9
25
25
% P
% Gln:
9
0
9
0
0
0
9
0
0
9
17
0
9
0
9
% Q
% Arg:
0
9
0
0
0
17
0
9
9
17
9
0
0
0
17
% R
% Ser:
0
9
34
0
0
0
0
17
25
9
34
25
0
9
17
% S
% Thr:
0
0
9
9
9
9
0
17
9
9
0
0
0
0
0
% T
% Val:
0
17
0
9
0
0
0
0
0
9
9
0
17
34
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
9
17
0
0
0
% W
% Tyr:
9
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _