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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ECSIT
All Species:
15.45
Human Site:
T254
Identified Species:
30.91
UniProt:
Q9BQ95
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BQ95
NP_001135936.1
431
49148
T254
V
P
L
P
K
D
S
T
G
A
A
D
P
P
Q
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001106441
430
49012
T254
V
P
L
P
K
D
S
T
G
A
A
D
P
P
Q
Dog
Lupus familis
XP_542054
433
48862
T254
M
P
S
S
K
D
S
T
G
A
A
D
P
T
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZH6
435
49780
T254
M
S
L
P
S
D
S
T
G
M
E
D
P
T
Q
Rat
Rattus norvegicus
Q5XIC2
434
49601
T253
M
S
L
P
S
E
S
T
G
I
E
D
P
T
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520260
452
51596
A282
T
D
V
P
E
G
P
A
G
A
S
A
L
F
Q
Chicken
Gallus gallus
Frog
Xenopus laevis
A2VD95
410
47567
D238
M
P
Y
T
E
K
C
D
D
G
K
E
Q
E
H
Zebra Danio
Brachydanio rerio
Q08CK1
452
52168
E267
Y
P
S
T
D
I
T
E
T
G
E
E
I
T
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9U6M0
409
47046
I235
T
S
E
L
K
D
A
I
D
D
T
W
I
V
S
Honey Bee
Apis mellifera
XP_001122337
353
41789
I203
T
K
D
I
P
D
A
I
D
D
T
W
I
V
S
Nematode Worm
Caenorhab. elegans
NP_500631
350
40617
S200
M
S
R
D
A
A
S
S
I
S
L
L
K
L
S
Sea Urchin
Strong. purpuratus
XP_794444
398
45864
G229
P
I
K
L
S
E
I
G
L
K
R
I
S
E
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
92.5
78.2
N.A.
73.3
72.5
N.A.
59.9
N.A.
45.7
48.4
N.A.
32.7
27.8
27.8
33.6
Protein Similarity:
100
N.A.
95.8
86.8
N.A.
82
81.5
N.A.
70.5
N.A.
63.5
63.5
N.A.
53.5
48.4
46.8
52.2
P-Site Identity:
100
N.A.
100
66.6
N.A.
60
53.3
N.A.
26.6
N.A.
6.6
6.6
N.A.
13.3
6.6
6.6
0
P-Site Similarity:
100
N.A.
100
80
N.A.
66.6
66.6
N.A.
46.6
N.A.
26.6
26.6
N.A.
20
13.3
26.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
9
9
17
9
0
34
25
9
0
0
0
% A
% Cys:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
9
9
9
50
0
9
25
17
0
42
0
0
0
% D
% Glu:
0
0
9
0
17
17
0
9
0
0
25
17
0
17
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% F
% Gly:
0
0
0
0
0
9
0
9
50
17
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% H
% Ile:
0
9
0
9
0
9
9
17
9
9
0
9
25
0
0
% I
% Lys:
0
9
9
0
34
9
0
0
0
9
9
0
9
0
0
% K
% Leu:
0
0
34
17
0
0
0
0
9
0
9
9
9
9
0
% L
% Met:
42
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
9
42
0
42
9
0
9
0
0
0
0
0
42
17
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
42
% Q
% Arg:
0
0
9
0
0
0
0
0
0
0
9
0
0
0
9
% R
% Ser:
0
34
17
9
25
0
50
9
0
9
9
0
9
0
25
% S
% Thr:
25
0
0
17
0
0
9
42
9
0
17
0
0
34
0
% T
% Val:
17
0
9
0
0
0
0
0
0
0
0
0
0
17
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
17
0
0
0
% W
% Tyr:
9
0
9
0
0
0
0
0
0
0
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _