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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ECSIT All Species: 15.45
Human Site: T254 Identified Species: 30.91
UniProt: Q9BQ95 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BQ95 NP_001135936.1 431 49148 T254 V P L P K D S T G A A D P P Q
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001106441 430 49012 T254 V P L P K D S T G A A D P P Q
Dog Lupus familis XP_542054 433 48862 T254 M P S S K D S T G A A D P T E
Cat Felis silvestris
Mouse Mus musculus Q9QZH6 435 49780 T254 M S L P S D S T G M E D P T Q
Rat Rattus norvegicus Q5XIC2 434 49601 T253 M S L P S E S T G I E D P T Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520260 452 51596 A282 T D V P E G P A G A S A L F Q
Chicken Gallus gallus
Frog Xenopus laevis A2VD95 410 47567 D238 M P Y T E K C D D G K E Q E H
Zebra Danio Brachydanio rerio Q08CK1 452 52168 E267 Y P S T D I T E T G E E I T R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9U6M0 409 47046 I235 T S E L K D A I D D T W I V S
Honey Bee Apis mellifera XP_001122337 353 41789 I203 T K D I P D A I D D T W I V S
Nematode Worm Caenorhab. elegans NP_500631 350 40617 S200 M S R D A A S S I S L L K L S
Sea Urchin Strong. purpuratus XP_794444 398 45864 G229 P I K L S E I G L K R I S E Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 92.5 78.2 N.A. 73.3 72.5 N.A. 59.9 N.A. 45.7 48.4 N.A. 32.7 27.8 27.8 33.6
Protein Similarity: 100 N.A. 95.8 86.8 N.A. 82 81.5 N.A. 70.5 N.A. 63.5 63.5 N.A. 53.5 48.4 46.8 52.2
P-Site Identity: 100 N.A. 100 66.6 N.A. 60 53.3 N.A. 26.6 N.A. 6.6 6.6 N.A. 13.3 6.6 6.6 0
P-Site Similarity: 100 N.A. 100 80 N.A. 66.6 66.6 N.A. 46.6 N.A. 26.6 26.6 N.A. 20 13.3 26.6 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 9 9 17 9 0 34 25 9 0 0 0 % A
% Cys: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % C
% Asp: 0 9 9 9 9 50 0 9 25 17 0 42 0 0 0 % D
% Glu: 0 0 9 0 17 17 0 9 0 0 25 17 0 17 9 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % F
% Gly: 0 0 0 0 0 9 0 9 50 17 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % H
% Ile: 0 9 0 9 0 9 9 17 9 9 0 9 25 0 0 % I
% Lys: 0 9 9 0 34 9 0 0 0 9 9 0 9 0 0 % K
% Leu: 0 0 34 17 0 0 0 0 9 0 9 9 9 9 0 % L
% Met: 42 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 9 42 0 42 9 0 9 0 0 0 0 0 42 17 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 42 % Q
% Arg: 0 0 9 0 0 0 0 0 0 0 9 0 0 0 9 % R
% Ser: 0 34 17 9 25 0 50 9 0 9 9 0 9 0 25 % S
% Thr: 25 0 0 17 0 0 9 42 9 0 17 0 0 34 0 % T
% Val: 17 0 9 0 0 0 0 0 0 0 0 0 0 17 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 17 0 0 0 % W
% Tyr: 9 0 9 0 0 0 0 0 0 0 0 0 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _