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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ECSIT
All Species:
21.21
Human Site:
Y245
Identified Species:
42.42
UniProt:
Q9BQ95
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BQ95
NP_001135936.1
431
49148
Y245
L
S
A
R
V
T
I
Y
Q
V
P
L
P
K
D
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001106441
430
49012
Y245
L
S
A
R
V
T
I
Y
Q
V
P
L
P
K
D
Dog
Lupus familis
XP_542054
433
48862
Y245
L
N
A
T
V
T
I
Y
Q
M
P
S
S
K
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZH6
435
49780
Y245
L
S
A
K
V
T
V
Y
Q
M
S
L
P
S
D
Rat
Rattus norvegicus
Q5XIC2
434
49601
Y244
L
S
A
K
V
T
V
Y
Q
M
S
L
P
S
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520260
452
51596
Q273
S
A
R
V
T
V
Y
Q
V
T
D
V
P
E
G
Chicken
Gallus gallus
Frog
Xenopus laevis
A2VD95
410
47567
H229
L
D
S
R
V
A
V
H
Q
M
P
Y
T
E
K
Zebra Danio
Brachydanio rerio
Q08CK1
452
52168
Y258
L
D
A
K
I
T
I
Y
Q
Y
P
S
T
D
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9U6M0
409
47046
F226
L
R
S
K
I
T
V
F
E
T
S
E
L
K
D
Honey Bee
Apis mellifera
XP_001122337
353
41789
Y194
V
Q
A
N
T
I
V
Y
K
T
K
D
I
P
D
Nematode Worm
Caenorhab. elegans
NP_500631
350
40617
K191
E
L
A
G
I
A
L
K
M
M
S
R
D
A
A
Sea Urchin
Strong. purpuratus
XP_794444
398
45864
S220
P
L
P
K
E
M
P
S
D
P
I
K
L
S
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
92.5
78.2
N.A.
73.3
72.5
N.A.
59.9
N.A.
45.7
48.4
N.A.
32.7
27.8
27.8
33.6
Protein Similarity:
100
N.A.
95.8
86.8
N.A.
82
81.5
N.A.
70.5
N.A.
63.5
63.5
N.A.
53.5
48.4
46.8
52.2
P-Site Identity:
100
N.A.
100
66.6
N.A.
66.6
60
N.A.
6.6
N.A.
33.3
46.6
N.A.
26.6
20
6.6
0
P-Site Similarity:
100
N.A.
100
80
N.A.
86.6
86.6
N.A.
26.6
N.A.
66.6
60
N.A.
66.6
40
26.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
67
0
0
17
0
0
0
0
0
0
0
9
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
17
0
0
0
0
0
0
9
0
9
9
9
9
50
% D
% Glu:
9
0
0
0
9
0
0
0
9
0
0
9
0
17
17
% E
% Phe:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
9
% G
% His:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
25
9
34
0
0
0
9
0
9
0
9
% I
% Lys:
0
0
0
42
0
0
0
9
9
0
9
9
0
34
9
% K
% Leu:
67
17
0
0
0
0
9
0
0
0
0
34
17
0
0
% L
% Met:
0
0
0
0
0
9
0
0
9
42
0
0
0
0
0
% M
% Asn:
0
9
0
9
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
9
0
9
0
0
0
9
0
0
9
42
0
42
9
0
% P
% Gln:
0
9
0
0
0
0
0
9
59
0
0
0
0
0
0
% Q
% Arg:
0
9
9
25
0
0
0
0
0
0
0
9
0
0
0
% R
% Ser:
9
34
17
0
0
0
0
9
0
0
34
17
9
25
0
% S
% Thr:
0
0
0
9
17
59
0
0
0
25
0
0
17
0
0
% T
% Val:
9
0
0
9
50
9
42
0
9
17
0
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
9
59
0
9
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _