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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ECSIT
All Species:
22.12
Human Site:
Y327
Identified Species:
44.24
UniProt:
Q9BQ95
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BQ95
NP_001135936.1
431
49148
Y327
T
P
E
E
W
N
L
Y
Y
P
M
Q
L
D
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001106441
430
49012
Y327
T
P
E
E
W
N
L
Y
Y
P
M
Q
L
D
L
Dog
Lupus familis
XP_542054
433
48862
Y327
I
P
E
E
W
N
L
Y
Y
P
M
Q
L
D
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZH6
435
49780
Y327
I
P
E
E
W
E
L
Y
Y
P
Q
K
L
D
L
Rat
Rattus norvegicus
Q5XIC2
434
49601
Y326
I
P
E
E
W
N
L
Y
Y
P
M
Q
L
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520260
452
51596
Y354
L
G
P
E
R
N
F
Y
C
P
M
Q
L
D
L
Chicken
Gallus gallus
Frog
Xenopus laevis
A2VD95
410
47567
Y309
I
D
N
E
R
S
F
Y
Y
P
L
S
L
D
I
Zebra Danio
Brachydanio rerio
Q08CK1
452
52168
F345
I
C
P
E
Q
S
L
F
F
P
Q
R
V
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9U6M0
409
47046
R313
I
E
V
P
F
F
G
R
A
P
P
R
R
H
N
Honey Bee
Apis mellifera
XP_001122337
353
41789
H268
E
D
Y
D
D
I
S
H
L
Q
I
P
F
W
E
Nematode Worm
Caenorhab. elegans
NP_500631
350
40617
E268
T
K
L
E
P
L
N
E
F
K
N
E
D
M
D
Sea Urchin
Strong. purpuratus
XP_794444
398
45864
E293
I
F
R
P
L
Y
V
E
G
P
Y
T
L
W
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
92.5
78.2
N.A.
73.3
72.5
N.A.
59.9
N.A.
45.7
48.4
N.A.
32.7
27.8
27.8
33.6
Protein Similarity:
100
N.A.
95.8
86.8
N.A.
82
81.5
N.A.
70.5
N.A.
63.5
63.5
N.A.
53.5
48.4
46.8
52.2
P-Site Identity:
100
N.A.
100
93.3
N.A.
73.3
93.3
N.A.
60
N.A.
40
26.6
N.A.
6.6
0
13.3
20
P-Site Similarity:
100
N.A.
100
93.3
N.A.
80
93.3
N.A.
60
N.A.
60
66.6
N.A.
20
20
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% A
% Cys:
0
9
0
0
0
0
0
0
9
0
0
0
0
0
0
% C
% Asp:
0
17
0
9
9
0
0
0
0
0
0
0
9
59
9
% D
% Glu:
9
9
42
75
0
9
0
17
0
0
0
9
0
9
9
% E
% Phe:
0
9
0
0
9
9
17
9
17
0
0
0
9
0
0
% F
% Gly:
0
9
0
0
0
0
9
0
9
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
9
0
0
0
0
0
9
0
% H
% Ile:
59
0
0
0
0
9
0
0
0
0
9
0
0
0
9
% I
% Lys:
0
9
0
0
0
0
0
0
0
9
0
9
0
0
0
% K
% Leu:
9
0
9
0
9
9
50
0
9
0
9
0
67
0
67
% L
% Met:
0
0
0
0
0
0
0
0
0
0
42
0
0
9
0
% M
% Asn:
0
0
9
0
0
42
9
0
0
0
9
0
0
0
9
% N
% Pro:
0
42
17
17
9
0
0
0
0
84
9
9
0
0
0
% P
% Gln:
0
0
0
0
9
0
0
0
0
9
17
42
0
0
0
% Q
% Arg:
0
0
9
0
17
0
0
9
0
0
0
17
9
0
0
% R
% Ser:
0
0
0
0
0
17
9
0
0
0
0
9
0
0
0
% S
% Thr:
25
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% T
% Val:
0
0
9
0
0
0
9
0
0
0
0
0
9
0
0
% V
% Trp:
0
0
0
0
42
0
0
0
0
0
0
0
0
17
0
% W
% Tyr:
0
0
9
0
0
9
0
59
50
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _