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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SOST All Species: 19.7
Human Site: S76 Identified Species: 54.17
UniProt: Q9BQB4 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BQB4 NP_079513.1 213 24031 S76 P F E T K D V S E Y S C R E L
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001113701 213 23921 S76 P F E T K D V S E Y S C R E L
Dog Lupus familis XP_548071 213 23757 S76 P F E T K D A S E Y S C R E L
Cat Felis silvestris
Mouse Mus musculus Q99P68 211 23424 S74 P Y D A K G V S E Y S C R E L
Rat Rattus norvegicus Q99P67 213 23956 S76 P Y D T K D V S E Y S C R E L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514836 206 23271 V71 G L D R N N R V Q V G C R E L
Chicken Gallus gallus Q6VYA3 206 23126 V71 G S D R N N R V Q V G C R E L
Frog Xenopus laevis NP_001080917 213 24340 H70 A L D R T N H H Q V G C R E L
Zebra Danio Brachydanio rerio XP_001340683 210 23847 S83 N T R T Y G A S E L S C R E L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 97.6 95.7 N.A. 86.8 89.6 N.A. 37.5 40.3 36.1 52.5 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 N.A. 97.6 96.2 N.A. 92 92.9 N.A. 59.6 59.1 54.4 63.8 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 N.A. 100 93.3 N.A. 73.3 86.6 N.A. 26.6 26.6 26.6 53.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 N.A. 100 93.3 N.A. 86.6 100 N.A. 46.6 46.6 46.6 53.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 0 0 12 0 0 23 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 % C
% Asp: 0 0 56 0 0 45 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 34 0 0 0 0 0 67 0 0 0 0 100 0 % E
% Phe: 0 34 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 23 0 0 0 0 23 0 0 0 0 34 0 0 0 0 % G
% His: 0 0 0 0 0 0 12 12 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 56 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 23 0 0 0 0 0 0 0 12 0 0 0 0 100 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 12 0 0 0 23 34 0 0 0 0 0 0 0 0 0 % N
% Pro: 56 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 34 0 0 0 0 0 0 % Q
% Arg: 0 0 12 34 0 0 23 0 0 0 0 0 100 0 0 % R
% Ser: 0 12 0 0 0 0 0 67 0 0 67 0 0 0 0 % S
% Thr: 0 12 0 56 12 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 45 23 0 34 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 23 0 0 12 0 0 0 0 56 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _