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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SOST
All Species:
19.7
Human Site:
S76
Identified Species:
54.17
UniProt:
Q9BQB4
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BQB4
NP_079513.1
213
24031
S76
P
F
E
T
K
D
V
S
E
Y
S
C
R
E
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001113701
213
23921
S76
P
F
E
T
K
D
V
S
E
Y
S
C
R
E
L
Dog
Lupus familis
XP_548071
213
23757
S76
P
F
E
T
K
D
A
S
E
Y
S
C
R
E
L
Cat
Felis silvestris
Mouse
Mus musculus
Q99P68
211
23424
S74
P
Y
D
A
K
G
V
S
E
Y
S
C
R
E
L
Rat
Rattus norvegicus
Q99P67
213
23956
S76
P
Y
D
T
K
D
V
S
E
Y
S
C
R
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514836
206
23271
V71
G
L
D
R
N
N
R
V
Q
V
G
C
R
E
L
Chicken
Gallus gallus
Q6VYA3
206
23126
V71
G
S
D
R
N
N
R
V
Q
V
G
C
R
E
L
Frog
Xenopus laevis
NP_001080917
213
24340
H70
A
L
D
R
T
N
H
H
Q
V
G
C
R
E
L
Zebra Danio
Brachydanio rerio
XP_001340683
210
23847
S83
N
T
R
T
Y
G
A
S
E
L
S
C
R
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.6
95.7
N.A.
86.8
89.6
N.A.
37.5
40.3
36.1
52.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
97.6
96.2
N.A.
92
92.9
N.A.
59.6
59.1
54.4
63.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
100
93.3
N.A.
73.3
86.6
N.A.
26.6
26.6
26.6
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
100
93.3
N.A.
86.6
100
N.A.
46.6
46.6
46.6
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
12
0
0
23
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
100
0
0
0
% C
% Asp:
0
0
56
0
0
45
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
34
0
0
0
0
0
67
0
0
0
0
100
0
% E
% Phe:
0
34
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
23
0
0
0
0
23
0
0
0
0
34
0
0
0
0
% G
% His:
0
0
0
0
0
0
12
12
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
56
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
23
0
0
0
0
0
0
0
12
0
0
0
0
100
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
12
0
0
0
23
34
0
0
0
0
0
0
0
0
0
% N
% Pro:
56
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
34
0
0
0
0
0
0
% Q
% Arg:
0
0
12
34
0
0
23
0
0
0
0
0
100
0
0
% R
% Ser:
0
12
0
0
0
0
0
67
0
0
67
0
0
0
0
% S
% Thr:
0
12
0
56
12
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
45
23
0
34
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
23
0
0
12
0
0
0
0
56
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _