KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VKORC1
All Species:
10.3
Human Site:
S149
Identified Species:
22.67
UniProt:
Q9BQB6
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BQB6
NP_076869.1
163
18235
S149
N
V
S
L
M
W
L
S
F
R
K
V
Q
E
P
Chimpanzee
Pan troglodytes
XP_001155391
65
7365
P58
S
F
Q
K
V
Q
E
P
Q
G
K
A
K
S
Y
Rhesus Macaque
Macaca mulatta
XP_001088069
176
19803
N156
N
F
L
L
L
I
I
N
Y
K
R
L
V
Y
L
Dog
Lupus familis
XP_536902
163
17992
S149
N
V
G
L
V
V
L
S
F
R
K
V
Q
E
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9CRC0
161
17750
S149
N
V
G
L
M
L
L
S
F
Q
K
V
P
E
H
Rat
Rattus norvegicus
Q6TEK4
161
17765
S149
N
A
G
L
M
L
L
S
F
Q
K
V
P
E
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515456
187
20205
R171
F
Y
S
G
G
G
L
R
N
G
G
S
A
A
S
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001336460
171
18827
N154
N
F
A
L
L
Y
T
N
L
K
R
R
T
G
L
Tiger Blowfish
Takifugu rubipres
NP_001027838
163
18325
N148
N
F
V
L
L
F
T
N
L
K
R
R
R
A
I
Fruit Fly
Dros. melanogaster
NP_001014533
152
17549
R145
W
L
F
Q
E
V
L
R
R
Y
R
R
L
Y
M
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001202176
143
15775
L136
T
Y
V
V
N
A
A
L
F
F
I
N
L
I
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
34.9
44.8
90.8
N.A.
84.6
82.8
N.A.
49.2
N.A.
N.A.
52.6
53.3
36.2
N.A.
N.A.
42.3
Protein Similarity:
100
38
66.4
94.4
N.A.
91.4
90.1
N.A.
59.3
N.A.
N.A.
70.1
75.4
53.9
N.A.
N.A.
66.8
P-Site Identity:
100
6.6
13.3
80
N.A.
66.6
60
N.A.
13.3
N.A.
N.A.
13.3
13.3
6.6
N.A.
N.A.
6.6
P-Site Similarity:
100
26.6
60
86.6
N.A.
73.3
66.6
N.A.
13.3
N.A.
N.A.
53.3
53.3
20
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
0
0
10
10
0
0
0
0
10
10
19
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
10
0
10
0
0
0
0
0
0
37
0
% E
% Phe:
10
37
10
0
0
10
0
0
46
10
0
0
0
0
0
% F
% Gly:
0
0
28
10
10
10
0
0
0
19
10
0
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
19
% H
% Ile:
0
0
0
0
0
10
10
0
0
0
10
0
0
10
10
% I
% Lys:
0
0
0
10
0
0
0
0
0
28
46
0
10
0
0
% K
% Leu:
0
10
10
64
28
19
55
10
19
0
0
10
19
0
19
% L
% Met:
0
0
0
0
28
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
64
0
0
0
10
0
0
28
10
0
0
10
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
10
0
0
0
0
19
0
19
% P
% Gln:
0
0
10
10
0
10
0
0
10
19
0
0
19
0
0
% Q
% Arg:
0
0
0
0
0
0
0
19
10
19
37
28
10
0
10
% R
% Ser:
10
0
19
0
0
0
0
37
0
0
0
10
0
10
10
% S
% Thr:
10
0
0
0
0
0
19
0
0
0
0
0
10
0
0
% T
% Val:
0
28
19
10
19
19
0
0
0
0
0
37
10
0
0
% V
% Trp:
10
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
19
0
0
0
10
0
0
10
10
0
0
0
19
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _