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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VKORC1
All Species:
19.7
Human Site:
S56
Identified Species:
43.33
UniProt:
Q9BQB6
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BQB6
NP_076869.1
163
18235
S56
I
S
C
S
R
V
F
S
S
R
W
G
R
G
F
Chimpanzee
Pan troglodytes
XP_001155391
65
7365
Rhesus Macaque
Macaca mulatta
XP_001088069
176
19803
A63
V
K
C
S
A
A
L
A
S
R
W
G
R
G
F
Dog
Lupus familis
XP_536902
163
17992
S56
I
S
C
S
R
V
F
S
S
R
W
G
R
G
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9CRC0
161
17750
S56
I
S
C
S
R
V
F
S
S
R
W
G
R
G
F
Rat
Rattus norvegicus
Q6TEK4
161
17765
S56
I
S
C
S
R
V
F
S
S
R
W
G
R
G
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515456
187
20205
S67
S
S
L
N
Q
P
N
S
V
F
G
L
L
F
Y
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001336460
171
18827
T61
V
S
C
S
K
V
F
T
S
R
W
G
R
G
F
Tiger Blowfish
Takifugu rubipres
NP_001027838
163
18325
R57
C
S
K
V
F
S
S
R
W
G
R
G
F
G
L
Fruit Fly
Dros. melanogaster
NP_001014533
152
17549
F54
N
I
S
C
S
L
V
F
K
S
G
Y
G
D
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001202176
143
15775
V45
G
T
I
S
C
S
K
V
F
T
S
K
Y
G
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
34.9
44.8
90.8
N.A.
84.6
82.8
N.A.
49.2
N.A.
N.A.
52.6
53.3
36.2
N.A.
N.A.
42.3
Protein Similarity:
100
38
66.4
94.4
N.A.
91.4
90.1
N.A.
59.3
N.A.
N.A.
70.1
75.4
53.9
N.A.
N.A.
66.8
P-Site Identity:
100
0
60
100
N.A.
100
100
N.A.
13.3
N.A.
N.A.
80
20
0
N.A.
N.A.
13.3
P-Site Similarity:
100
0
73.3
100
N.A.
100
100
N.A.
33.3
N.A.
N.A.
100
20
6.6
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
10
0
10
0
0
0
0
0
0
0
% A
% Cys:
10
0
55
10
10
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
10
0
46
10
10
10
0
0
10
10
55
% F
% Gly:
10
0
0
0
0
0
0
0
0
10
19
64
10
73
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
37
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
10
10
0
10
0
10
0
10
0
0
10
0
0
10
% K
% Leu:
0
0
10
0
0
10
10
0
0
0
0
10
10
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
10
0
0
10
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
37
0
0
10
0
55
10
0
55
0
0
% R
% Ser:
10
64
10
64
10
19
10
46
55
10
10
0
0
0
0
% S
% Thr:
0
10
0
0
0
0
0
10
0
10
0
0
0
0
0
% T
% Val:
19
0
0
10
0
46
10
10
10
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
10
0
55
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
10
10
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _