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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VKORC1
All Species:
21.52
Human Site:
S74
Identified Species:
47.33
UniProt:
Q9BQB6
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BQB6
NP_076869.1
163
18235
S74
E
H
V
L
G
Q
D
S
I
L
N
Q
S
N
S
Chimpanzee
Pan troglodytes
XP_001155391
65
7365
Rhesus Macaque
Macaca mulatta
XP_001088069
176
19803
G81
G
S
I
F
G
K
D
G
V
L
N
Q
P
N
S
Dog
Lupus familis
XP_536902
163
17992
S74
E
Q
V
L
G
Q
D
S
I
L
N
Q
S
N
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9CRC0
161
17750
S74
E
H
M
L
G
A
D
S
V
L
N
Q
S
N
S
Rat
Rattus norvegicus
Q6TEK4
161
17765
S74
E
H
V
L
G
A
D
S
I
L
N
Q
S
N
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515456
187
20205
S96
S
V
V
L
A
L
S
S
L
L
S
L
A
G
S
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001336460
171
18827
S79
Q
I
F
T
S
K
D
S
V
L
N
Q
P
N
S
Tiger Blowfish
Takifugu rubipres
NP_001027838
163
18325
S73
Q
Y
F
V
D
K
D
S
P
L
N
Q
P
N
S
Fruit Fly
Dros. melanogaster
NP_001014533
152
17549
V70
G
L
G
N
I
T
Q
V
N
A
P
N
G
A
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001202176
143
15775
L61
F
G
I
I
G
Q
I
L
G
E
D
N
I
L
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
34.9
44.8
90.8
N.A.
84.6
82.8
N.A.
49.2
N.A.
N.A.
52.6
53.3
36.2
N.A.
N.A.
42.3
Protein Similarity:
100
38
66.4
94.4
N.A.
91.4
90.1
N.A.
59.3
N.A.
N.A.
70.1
75.4
53.9
N.A.
N.A.
66.8
P-Site Identity:
100
0
46.6
93.3
N.A.
80
93.3
N.A.
33.3
N.A.
N.A.
46.6
46.6
0
N.A.
N.A.
13.3
P-Site Similarity:
100
0
66.6
93.3
N.A.
93.3
93.3
N.A.
53.3
N.A.
N.A.
66.6
73.3
0
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
19
0
0
0
10
0
0
10
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
0
64
0
0
0
10
0
0
0
0
% D
% Glu:
37
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% E
% Phe:
10
0
19
10
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
19
10
10
0
55
0
0
10
10
0
0
0
10
10
0
% G
% His:
0
28
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
19
10
10
0
10
0
28
0
0
0
10
0
10
% I
% Lys:
0
0
0
0
0
28
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
10
0
46
0
10
0
10
10
73
0
10
0
10
0
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
0
0
10
0
64
19
0
64
10
% N
% Pro:
0
0
0
0
0
0
0
0
10
0
10
0
28
0
0
% P
% Gln:
19
10
0
0
0
28
10
0
0
0
0
64
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
10
10
0
0
10
0
10
64
0
0
10
0
37
0
73
% S
% Thr:
0
0
0
10
0
10
0
0
0
0
0
0
0
0
0
% T
% Val:
0
10
37
10
0
0
0
10
28
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _