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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DPH2 All Species: 19.7
Human Site: S178 Identified Species: 30.95
UniProt: Q9BQC3 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BQC3 NP_001375.2 489 52083 S178 R Y L D L L V S S P A F P Q P
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_532611 487 51822 S178 R Y L D L L V S S P A L P L P
Cat Felis silvestris
Mouse Mus musculus Q9CR25 489 52346 S178 K Y Q D L L I S R P A L P L P
Rat Rattus norvegicus Q568Y2 489 52306 S178 K Y Q D L L I S S P A L P L P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZKI2 477 52145 P171 K Q L C H E Y P N I I F S E V
Frog Xenopus laevis Q6DE00 478 52667 I171 L G E L A K R I R S A Y P N V
Zebra Danio Brachydanio rerio A4QN59 498 55134 S177 V Y P N V V V S R L K T D H S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650402 469 52077 K175 V Y G E K L K K Q L S E I L E
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q09454 476 52936 V192 V L P G N R H V E C S L L P S
Sea Urchin Strong. purpuratus XP_786110 552 60545 S178 D Y P N A V F S S I D S T P T
Poplar Tree Populus trichocarpa XP_002326199 496 54716 S158 A A S T L S G S K T K T V F H
Maize Zea mays NP_001146073 514 56668 S171 Q Y A E V L C S V M S P S S S
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_191522 491 54825 S159 S K T D S Q L S V A N V L C S
Baker's Yeast Sacchar. cerevisiae P32461 534 59757 T192 L K G D L H Y T N I I Y S Q V
Red Bread Mold Neurospora crassa Q7S5C0 602 65317 A245 G G Y V N L L A T E I V H N P
Conservation
Percent
Protein Identity: 100 N.A. N.A. 88.3 N.A. 83.6 84.8 N.A. N.A. 47.4 44.3 38.7 N.A. 29.6 N.A. 29.8 35.5
Protein Similarity: 100 N.A. N.A. 91.6 N.A. 88.9 89.5 N.A. N.A. 60.3 61.1 56.6 N.A. 47.6 N.A. 48.2 51.2
P-Site Identity: 100 N.A. N.A. 86.6 N.A. 60 66.6 N.A. N.A. 13.3 13.3 20 N.A. 13.3 N.A. 0 20
P-Site Similarity: 100 N.A. N.A. 86.6 N.A. 73.3 80 N.A. N.A. 33.3 20 40 N.A. 26.6 N.A. 6.6 33.3
Percent
Protein Identity: 27 26 N.A. 26.2 25.6 24.7
Protein Similarity: 44.1 43.3 N.A. 45.2 40.8 37.2
P-Site Identity: 13.3 20 N.A. 13.3 20 13.3
P-Site Similarity: 13.3 46.6 N.A. 20 40 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 7 7 0 14 0 0 7 0 7 34 0 0 0 0 % A
% Cys: 0 0 0 7 0 0 7 0 0 7 0 0 0 7 0 % C
% Asp: 7 0 0 40 0 0 0 0 0 0 7 0 7 0 0 % D
% Glu: 0 0 7 14 0 7 0 0 7 7 0 7 0 7 7 % E
% Phe: 0 0 0 0 0 0 7 0 0 0 0 14 0 7 0 % F
% Gly: 7 14 14 7 0 0 7 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 7 7 7 0 0 0 0 0 7 7 7 % H
% Ile: 0 0 0 0 0 0 14 7 0 20 20 0 7 0 0 % I
% Lys: 20 14 0 0 7 7 7 7 7 0 14 0 0 0 0 % K
% Leu: 14 7 20 7 40 47 14 0 0 14 0 27 14 27 0 % L
% Met: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % M
% Asn: 0 0 0 14 14 0 0 0 14 0 7 0 0 14 0 % N
% Pro: 0 0 20 0 0 0 0 7 0 27 0 7 34 14 34 % P
% Gln: 7 7 14 0 0 7 0 0 7 0 0 0 0 14 0 % Q
% Arg: 14 0 0 0 0 7 7 0 20 0 0 0 0 0 0 % R
% Ser: 7 0 7 0 7 7 0 60 27 7 20 7 20 7 27 % S
% Thr: 0 0 7 7 0 0 0 7 7 7 0 14 7 0 7 % T
% Val: 20 0 0 7 14 14 20 7 14 0 0 14 7 0 20 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 54 7 0 0 0 14 0 0 0 0 14 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _