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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DPH2
All Species:
12.73
Human Site:
S188
Identified Species:
20
UniProt:
Q9BQC3
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BQC3
NP_001375.2
489
52083
S188
A
F
P
Q
P
V
G
S
L
S
P
E
P
M
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532611
487
51822
S188
A
L
P
L
P
A
G
S
C
S
P
E
P
E
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9CR25
489
52346
S188
A
L
P
L
P
V
G
S
P
S
S
Q
P
E
S
Rat
Rattus norvegicus
Q568Y2
489
52306
S188
A
L
P
L
P
V
G
S
L
S
S
Q
P
E
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZKI2
477
52145
G181
I
F
S
E
V
V
C
G
D
A
P
S
P
T
L
Frog
Xenopus laevis
Q6DE00
478
52667
S181
A
Y
P
N
V
I
F
S
K
L
T
S
C
G
E
Zebra Danio
Brachydanio rerio
A4QN59
498
55134
A187
K
T
D
H
S
C
G
A
E
L
I
Q
D
S
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650402
469
52077
E185
S
E
I
L
E
P
K
E
L
L
L
E
L
F
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09454
476
52936
V202
S
L
L
P
S
E
D
V
L
K
Q
N
R
Q
N
Sea Urchin
Strong. purpuratus
XP_786110
552
60545
P188
D
S
T
P
T
V
S
P
Q
D
T
R
T
G
S
Poplar Tree
Populus trichocarpa
XP_002326199
496
54716
E168
K
T
V
F
H
F
A
E
V
M
C
P
L
I
N
Maize
Zea mays
NP_001146073
514
56668
E181
S
P
S
S
S
T
T
E
E
N
K
I
P
Q
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_191522
491
54825
S169
N
V
L
C
S
F
I
S
P
S
K
D
P
R
E
Baker's Yeast
Sacchar. cerevisiae
P32461
534
59757
S202
I
Y
S
Q
V
N
T
S
A
V
E
E
K
F
V
Red Bread Mold
Neurospora crassa
Q7S5C0
602
65317
R255
I
V
H
N
P
M
G
R
I
P
N
R
K
V
V
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
88.3
N.A.
83.6
84.8
N.A.
N.A.
47.4
44.3
38.7
N.A.
29.6
N.A.
29.8
35.5
Protein Similarity:
100
N.A.
N.A.
91.6
N.A.
88.9
89.5
N.A.
N.A.
60.3
61.1
56.6
N.A.
47.6
N.A.
48.2
51.2
P-Site Identity:
100
N.A.
N.A.
66.6
N.A.
53.3
60
N.A.
N.A.
26.6
20
6.6
N.A.
20
N.A.
6.6
6.6
P-Site Similarity:
100
N.A.
N.A.
66.6
N.A.
60
66.6
N.A.
N.A.
40
33.3
20
N.A.
26.6
N.A.
13.3
6.6
Percent
Protein Identity:
27
26
N.A.
26.2
25.6
24.7
Protein Similarity:
44.1
43.3
N.A.
45.2
40.8
37.2
P-Site Identity:
0
6.6
N.A.
20
20
13.3
P-Site Similarity:
13.3
20
N.A.
26.6
26.6
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
34
0
0
0
0
7
7
7
7
7
0
0
0
0
0
% A
% Cys:
0
0
0
7
0
7
7
0
7
0
7
0
7
0
7
% C
% Asp:
7
0
7
0
0
0
7
0
7
7
0
7
7
0
0
% D
% Glu:
0
7
0
7
7
7
0
20
14
0
7
27
0
20
14
% E
% Phe:
0
14
0
7
0
14
7
0
0
0
0
0
0
14
0
% F
% Gly:
0
0
0
0
0
0
40
7
0
0
0
0
0
14
0
% G
% His:
0
0
7
7
7
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
20
0
7
0
0
7
7
0
7
0
7
7
0
7
0
% I
% Lys:
14
0
0
0
0
0
7
0
7
7
14
0
14
0
0
% K
% Leu:
0
27
14
27
0
0
0
0
27
20
7
0
14
0
7
% L
% Met:
0
0
0
0
0
7
0
0
0
7
0
0
0
7
0
% M
% Asn:
7
0
0
14
0
7
0
0
0
7
7
7
0
0
14
% N
% Pro:
0
7
34
14
34
7
0
7
14
7
20
7
47
0
20
% P
% Gln:
0
0
0
14
0
0
0
0
7
0
7
20
0
14
0
% Q
% Arg:
0
0
0
0
0
0
0
7
0
0
0
14
7
7
0
% R
% Ser:
20
7
20
7
27
0
7
47
0
34
14
14
0
7
27
% S
% Thr:
0
14
7
0
7
7
14
0
0
0
14
0
7
7
0
% T
% Val:
0
14
7
0
20
34
0
7
7
7
0
0
0
7
14
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
14
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _