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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DPH2 All Species: 10.91
Human Site: S190 Identified Species: 17.14
UniProt: Q9BQC3 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BQC3 NP_001375.2 489 52083 S190 P Q P V G S L S P E P M P L E
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_532611 487 51822 S190 P L P A G S C S P E P E P L E
Cat Felis silvestris
Mouse Mus musculus Q9CR25 489 52346 S190 P L P V G S P S S Q P E S L E
Rat Rattus norvegicus Q568Y2 489 52306 S190 P L P V G S L S S Q P E S L E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZKI2 477 52145 A183 S E V V C G D A P S P T L P G
Frog Xenopus laevis Q6DE00 478 52667 L183 P N V I F S K L T S C G E T A
Zebra Danio Brachydanio rerio A4QN59 498 55134 L189 D H S C G A E L I Q D S C V D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650402 469 52077 L187 I L E P K E L L L E L F P P I
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q09454 476 52936 K204 L P S E D V L K Q N R Q N I Y
Sea Urchin Strong. purpuratus XP_786110 552 60545 D190 T P T V S P Q D T R T G S S L
Poplar Tree Populus trichocarpa XP_002326199 496 54716 M170 V F H F A E V M C P L I N P P
Maize Zea mays NP_001146073 514 56668 N183 S S S T T E E N K I P Q S S G
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_191522 491 54825 S171 L C S F I S P S K D P R E S M
Baker's Yeast Sacchar. cerevisiae P32461 534 59757 V204 S Q V N T S A V E E K F V T I
Red Bread Mold Neurospora crassa Q7S5C0 602 65317 P257 H N P M G R I P N R K V V D A
Conservation
Percent
Protein Identity: 100 N.A. N.A. 88.3 N.A. 83.6 84.8 N.A. N.A. 47.4 44.3 38.7 N.A. 29.6 N.A. 29.8 35.5
Protein Similarity: 100 N.A. N.A. 91.6 N.A. 88.9 89.5 N.A. N.A. 60.3 61.1 56.6 N.A. 47.6 N.A. 48.2 51.2
P-Site Identity: 100 N.A. N.A. 73.3 N.A. 60 66.6 N.A. N.A. 20 13.3 6.6 N.A. 20 N.A. 6.6 6.6
P-Site Similarity: 100 N.A. N.A. 73.3 N.A. 66.6 73.3 N.A. N.A. 33.3 20 33.3 N.A. 20 N.A. 13.3 6.6
Percent
Protein Identity: 27 26 N.A. 26.2 25.6 24.7
Protein Similarity: 44.1 43.3 N.A. 45.2 40.8 37.2
P-Site Identity: 0 6.6 N.A. 20 20 13.3
P-Site Similarity: 13.3 13.3 N.A. 26.6 20 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 7 7 7 7 7 0 0 0 0 0 0 14 % A
% Cys: 0 7 0 7 7 0 7 0 7 0 7 0 7 0 0 % C
% Asp: 7 0 0 0 7 0 7 7 0 7 7 0 0 7 7 % D
% Glu: 0 7 7 7 0 20 14 0 7 27 0 20 14 0 27 % E
% Phe: 0 7 0 14 7 0 0 0 0 0 0 14 0 0 0 % F
% Gly: 0 0 0 0 40 7 0 0 0 0 0 14 0 0 14 % G
% His: 7 7 7 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 7 0 0 7 7 0 7 0 7 7 0 7 0 7 14 % I
% Lys: 0 0 0 0 7 0 7 7 14 0 14 0 0 0 0 % K
% Leu: 14 27 0 0 0 0 27 20 7 0 14 0 7 27 7 % L
% Met: 0 0 0 7 0 0 0 7 0 0 0 7 0 0 7 % M
% Asn: 0 14 0 7 0 0 0 7 7 7 0 0 14 0 0 % N
% Pro: 34 14 34 7 0 7 14 7 20 7 47 0 20 20 7 % P
% Gln: 0 14 0 0 0 0 7 0 7 20 0 14 0 0 0 % Q
% Arg: 0 0 0 0 0 7 0 0 0 14 7 7 0 0 0 % R
% Ser: 20 7 27 0 7 47 0 34 14 14 0 7 27 20 0 % S
% Thr: 7 0 7 7 14 0 0 0 14 0 7 7 0 14 0 % T
% Val: 7 0 20 34 0 7 7 7 0 0 0 7 14 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _