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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DPH2 All Species: 16.36
Human Site: S235 Identified Species: 25.71
UniProt: Q9BQC3 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BQC3 NP_001375.2 489 52083 S235 P D L D P D L S R L L L G W A
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_532611 487 51822 S233 A D L D P D L S R L L L G W A
Cat Felis silvestris
Mouse Mus musculus Q9CR25 489 52346 S235 S S L D P D L S R L L L G W T
Rat Rattus norvegicus Q568Y2 489 52306 S235 P N L D P D L S R L L L G W T
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZKI2 477 52145 L222 V G A E G L A L T S F M L T W
Frog Xenopus laevis Q6DE00 478 52667 L225 V G G E G S T L N N L M L T W
Zebra Danio Brachydanio rerio A4QN59 498 55134 Q230 Y S I F Y I G Q E G L T L T N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650402 469 52077 N223 A D N Q R F A N L S L T A P A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q09454 476 52936 P240 F P N S P L L P I W L L S Y P
Sea Urchin Strong. purpuratus XP_786110 552 60545 T241 D Q K D E E R T K G E V E G K
Poplar Tree Populus trichocarpa XP_002326199 496 54716 Y225 S G Q K M E D Y L L L W I G S
Maize Zea mays NP_001146073 514 56668 K236 W N I S V E E K M E D Y F I F
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_191522 491 54825 G223 D Y L L F W I G S D S S A F A
Baker's Yeast Sacchar. cerevisiae P32461 534 59757 Y248 D N I S P E D Y H L F H L T T
Red Bread Mold Neurospora crassa Q7S5C0 602 65317 A297 H I S Q P P T A L L L A L C S
Conservation
Percent
Protein Identity: 100 N.A. N.A. 88.3 N.A. 83.6 84.8 N.A. N.A. 47.4 44.3 38.7 N.A. 29.6 N.A. 29.8 35.5
Protein Similarity: 100 N.A. N.A. 91.6 N.A. 88.9 89.5 N.A. N.A. 60.3 61.1 56.6 N.A. 47.6 N.A. 48.2 51.2
P-Site Identity: 100 N.A. N.A. 93.3 N.A. 80 86.6 N.A. N.A. 0 6.6 6.6 N.A. 20 N.A. 26.6 6.6
P-Site Similarity: 100 N.A. N.A. 93.3 N.A. 80 93.3 N.A. N.A. 13.3 20 13.3 N.A. 26.6 N.A. 33.3 33.3
Percent
Protein Identity: 27 26 N.A. 26.2 25.6 24.7
Protein Similarity: 44.1 43.3 N.A. 45.2 40.8 37.2
P-Site Identity: 13.3 0 N.A. 13.3 13.3 20
P-Site Similarity: 26.6 20 N.A. 26.6 33.3 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 14 0 7 0 0 0 14 7 0 0 0 7 14 0 27 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % C
% Asp: 20 20 0 34 0 27 14 0 0 7 7 0 0 0 0 % D
% Glu: 0 0 0 14 7 27 7 0 7 7 7 0 7 0 0 % E
% Phe: 7 0 0 7 7 7 0 0 0 0 14 0 7 7 7 % F
% Gly: 0 20 7 0 14 0 7 7 0 14 0 0 27 14 0 % G
% His: 7 0 0 0 0 0 0 0 7 0 0 7 0 0 0 % H
% Ile: 0 7 20 0 0 7 7 0 7 0 0 0 7 7 0 % I
% Lys: 0 0 7 7 0 0 0 7 7 0 0 0 0 0 7 % K
% Leu: 0 0 34 7 0 14 34 14 20 47 67 34 34 0 0 % L
% Met: 0 0 0 0 7 0 0 0 7 0 0 14 0 0 0 % M
% Asn: 0 20 14 0 0 0 0 7 7 7 0 0 0 0 7 % N
% Pro: 14 7 0 0 47 7 0 7 0 0 0 0 0 7 7 % P
% Gln: 0 7 7 14 0 0 0 7 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 7 0 7 0 27 0 0 0 0 0 0 % R
% Ser: 14 14 7 20 0 7 0 27 7 14 7 7 7 0 14 % S
% Thr: 0 0 0 0 0 0 14 7 7 0 0 14 0 27 20 % T
% Val: 14 0 0 0 7 0 0 0 0 0 0 7 0 0 0 % V
% Trp: 7 0 0 0 0 7 0 0 0 7 0 7 0 27 14 % W
% Tyr: 7 7 0 0 7 0 0 14 0 0 0 7 0 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _