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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DPH2 All Species: 13.94
Human Site: S426 Identified Species: 21.9
UniProt: Q9BQC3 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.21
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BQC3 NP_001375.2 489 52083 S426 P P P A W K S S N D H G S L A
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_532611 487 51822 S424 P P P A W K P S N D P G C L D
Cat Felis silvestris
Mouse Mus musculus Q9CR25 489 52346 S426 P P P P W K S S D D T R C S A
Rat Rattus norvegicus Q568Y2 489 52306 S426 P P P P W K S S D D T K C S A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZKI2 477 52145 Q412 L C D P L A P Q P P S S T T L
Frog Xenopus laevis Q6DE00 478 52667 E415 L T V A E T L E K D S D T S L
Zebra Danio Brachydanio rerio A4QN59 498 55134 H427 T N S S E M M H N S E T S S L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650402 469 52077 R400 S L V S G R L R G A V N D S L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q09454 476 52936 I412 A A G D F S L I S G K V R V Q
Sea Urchin Strong. purpuratus XP_786110 552 60545 S490 D N R L M G R S C D A G A L V
Poplar Tree Populus trichocarpa XP_002326199 496 54716 E424 E K K E E E N E G V L A L A N
Maize Zea mays NP_001146073 514 56668 E448 L A L A E V T E K A L S I Q N
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_191522 491 54825 T420 A K N G E E D T G E T M T L V
Baker's Yeast Sacchar. cerevisiae P32461 534 59757 T425 D T I S A S T T S D E P E F D
Red Bread Mold Neurospora crassa Q7S5C0 602 65317 D521 P K S A K K E D S S D K P D A
Conservation
Percent
Protein Identity: 100 N.A. N.A. 88.3 N.A. 83.6 84.8 N.A. N.A. 47.4 44.3 38.7 N.A. 29.6 N.A. 29.8 35.5
Protein Similarity: 100 N.A. N.A. 91.6 N.A. 88.9 89.5 N.A. N.A. 60.3 61.1 56.6 N.A. 47.6 N.A. 48.2 51.2
P-Site Identity: 100 N.A. N.A. 73.3 N.A. 60 60 N.A. N.A. 0 13.3 13.3 N.A. 0 N.A. 0 26.6
P-Site Similarity: 100 N.A. N.A. 73.3 N.A. 66.6 66.6 N.A. N.A. 6.6 20 20 N.A. 13.3 N.A. 20 33.3
Percent
Protein Identity: 27 26 N.A. 26.2 25.6 24.7
Protein Similarity: 44.1 43.3 N.A. 45.2 40.8 37.2
P-Site Identity: 0 6.6 N.A. 6.6 6.6 26.6
P-Site Similarity: 13.3 13.3 N.A. 33.3 33.3 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 14 14 0 34 7 7 0 0 0 14 7 7 7 7 27 % A
% Cys: 0 7 0 0 0 0 0 0 7 0 0 0 20 0 0 % C
% Asp: 14 0 7 7 0 0 7 7 14 47 7 7 7 7 14 % D
% Glu: 7 0 0 7 34 14 7 20 0 7 14 0 7 0 0 % E
% Phe: 0 0 0 0 7 0 0 0 0 0 0 0 0 7 0 % F
% Gly: 0 0 7 7 7 7 0 0 20 7 0 20 0 0 0 % G
% His: 0 0 0 0 0 0 0 7 0 0 7 0 0 0 0 % H
% Ile: 0 0 7 0 0 0 0 7 0 0 0 0 7 0 0 % I
% Lys: 0 20 7 0 7 34 0 0 14 0 7 14 0 0 0 % K
% Leu: 20 7 7 7 7 0 20 0 0 0 14 0 7 27 27 % L
% Met: 0 0 0 0 7 7 7 0 0 0 0 7 0 0 0 % M
% Asn: 0 14 7 0 0 0 7 0 20 0 0 7 0 0 14 % N
% Pro: 34 27 27 20 0 0 14 0 7 7 7 7 7 0 0 % P
% Gln: 0 0 0 0 0 0 0 7 0 0 0 0 0 7 7 % Q
% Arg: 0 0 7 0 0 7 7 7 0 0 0 7 7 0 0 % R
% Ser: 7 0 14 20 0 14 20 34 20 14 14 14 14 34 0 % S
% Thr: 7 14 0 0 0 7 14 14 0 0 20 7 20 7 0 % T
% Val: 0 0 14 0 0 7 0 0 0 7 7 7 0 7 14 % V
% Trp: 0 0 0 0 27 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _