KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DPH2
All Species:
3.64
Human Site:
S431
Identified Species:
5.71
UniProt:
Q9BQC3
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BQC3
NP_001375.2
489
52083
S431
K
S
S
N
D
H
G
S
L
A
L
T
P
R
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532611
487
51822
C429
K
P
S
N
D
P
G
C
L
D
L
N
L
R
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9CR25
489
52346
C431
K
S
S
D
D
T
R
C
S
A
L
I
P
R
P
Rat
Rattus norvegicus
Q568Y2
489
52306
C431
K
S
S
D
D
T
K
C
S
A
L
T
P
R
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZKI2
477
52145
T417
A
P
Q
P
P
S
S
T
T
L
A
C
R
D
Q
Frog
Xenopus laevis
Q6DE00
478
52667
T420
T
L
E
K
D
S
D
T
S
L
V
Q
R
N
S
Zebra Danio
Brachydanio rerio
A4QN59
498
55134
S432
M
M
H
N
S
E
T
S
S
L
V
L
R
N
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650402
469
52077
D405
R
L
R
G
A
V
N
D
S
L
E
T
G
G
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09454
476
52936
R417
S
L
I
S
G
K
V
R
V
Q
K
T
E
E
E
Sea Urchin
Strong. purpuratus
XP_786110
552
60545
A495
G
R
S
C
D
A
G
A
L
V
S
R
D
E
P
Poplar Tree
Populus trichocarpa
XP_002326199
496
54716
L429
E
N
E
G
V
L
A
L
A
N
A
T
E
K
A
Maize
Zea mays
NP_001146073
514
56668
I453
V
T
E
K
A
L
S
I
Q
N
Q
H
N
D
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_191522
491
54825
T425
E
D
T
G
E
T
M
T
L
V
Q
A
A
E
K
Baker's Yeast
Sacchar. cerevisiae
P32461
534
59757
E430
S
T
T
S
D
E
P
E
F
D
V
V
R
G
R
Red Bread Mold
Neurospora crassa
Q7S5C0
602
65317
P526
K
E
D
S
S
D
K
P
D
A
P
P
R
S
S
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
88.3
N.A.
83.6
84.8
N.A.
N.A.
47.4
44.3
38.7
N.A.
29.6
N.A.
29.8
35.5
Protein Similarity:
100
N.A.
N.A.
91.6
N.A.
88.9
89.5
N.A.
N.A.
60.3
61.1
56.6
N.A.
47.6
N.A.
48.2
51.2
P-Site Identity:
100
N.A.
N.A.
60
N.A.
60
66.6
N.A.
N.A.
0
6.6
13.3
N.A.
6.6
N.A.
6.6
33.3
P-Site Similarity:
100
N.A.
N.A.
60
N.A.
66.6
73.3
N.A.
N.A.
6.6
20
20
N.A.
13.3
N.A.
20
40
Percent
Protein Identity:
27
26
N.A.
26.2
25.6
24.7
Protein Similarity:
44.1
43.3
N.A.
45.2
40.8
37.2
P-Site Identity:
6.6
0
N.A.
6.6
6.6
13.3
P-Site Similarity:
26.6
6.6
N.A.
33.3
33.3
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
14
7
7
7
7
27
14
7
7
0
14
% A
% Cys:
0
0
0
7
0
0
0
20
0
0
0
7
0
0
0
% C
% Asp:
0
7
7
14
47
7
7
7
7
14
0
0
7
14
7
% D
% Glu:
14
7
20
0
7
14
0
7
0
0
7
0
14
20
7
% E
% Phe:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% F
% Gly:
7
0
0
20
7
0
20
0
0
0
0
0
7
14
0
% G
% His:
0
0
7
0
0
7
0
0
0
0
0
7
0
0
0
% H
% Ile:
0
0
7
0
0
0
0
7
0
0
0
7
0
0
0
% I
% Lys:
34
0
0
14
0
7
14
0
0
0
7
0
0
7
7
% K
% Leu:
0
20
0
0
0
14
0
7
27
27
27
7
7
0
0
% L
% Met:
7
7
0
0
0
0
7
0
0
0
0
0
0
0
0
% M
% Asn:
0
7
0
20
0
0
7
0
0
14
0
7
7
14
0
% N
% Pro:
0
14
0
7
7
7
7
7
0
0
7
7
20
0
34
% P
% Gln:
0
0
7
0
0
0
0
0
7
7
14
7
0
0
14
% Q
% Arg:
7
7
7
0
0
0
7
7
0
0
0
7
34
27
7
% R
% Ser:
14
20
34
20
14
14
14
14
34
0
7
0
0
7
14
% S
% Thr:
7
14
14
0
0
20
7
20
7
0
0
34
0
0
0
% T
% Val:
7
0
0
0
7
7
7
0
7
14
20
7
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _