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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DPH2 All Species: 8.48
Human Site: S75 Identified Species: 13.33
UniProt: Q9BQC3 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BQC3 NP_001375.2 489 52083 S75 R L E E T T G S K M F I L G D
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_532611 487 51822 S75 R L E G T T G S K M F I L G D
Cat Felis silvestris
Mouse Mus musculus Q9CR25 489 52346 A75 R L E E V T G A K M F I L G D
Rat Rattus norvegicus Q568Y2 489 52306 S75 R L E E V T G S K M F I L G D
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZKI2 477 52145 A74 R M E E V T G A E M Y V L G D
Frog Xenopus laevis Q6DE00 478 52667 A79 K L E E A T G A K T Y I L G D
Zebra Danio Brachydanio rerio A4QN59 498 55134 A75 E I E D K T K A K T Y I L G D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650402 469 52077 V83 E L L A P E D V K V F I L A D
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q09454 476 52936 K88 R F R S E S A K K T F V L A D
Sea Urchin Strong. purpuratus XP_786110 552 60545 A76 V L Q S K I S A T V F I L G D
Poplar Tree Populus trichocarpa XP_002326199 496 54716 V56 K L K E Q I G V S L F V M A D
Maize Zea mays NP_001146073 514 56668 V58 S G G A D S G V R V F V M A D
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_191522 491 54825 V57 R L L T D R E V R F F V M A D
Baker's Yeast Sacchar. cerevisiae P32461 534 59757 I93 S K F P H G K I K F W V L A D
Red Bread Mold Neurospora crassa Q7S5C0 602 65317 R143 V E S Q P K A R R V Y V L A D
Conservation
Percent
Protein Identity: 100 N.A. N.A. 88.3 N.A. 83.6 84.8 N.A. N.A. 47.4 44.3 38.7 N.A. 29.6 N.A. 29.8 35.5
Protein Similarity: 100 N.A. N.A. 91.6 N.A. 88.9 89.5 N.A. N.A. 60.3 61.1 56.6 N.A. 47.6 N.A. 48.2 51.2
P-Site Identity: 100 N.A. N.A. 93.3 N.A. 86.6 93.3 N.A. N.A. 60 66.6 46.6 N.A. 40 N.A. 33.3 40
P-Site Similarity: 100 N.A. N.A. 93.3 N.A. 93.3 93.3 N.A. N.A. 93.3 86.6 73.3 N.A. 46.6 N.A. 46.6 60
Percent
Protein Identity: 27 26 N.A. 26.2 25.6 24.7
Protein Similarity: 44.1 43.3 N.A. 45.2 40.8 37.2
P-Site Identity: 33.3 20 N.A. 26.6 20 13.3
P-Site Similarity: 66.6 53.3 N.A. 46.6 33.3 46.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 14 7 0 14 34 0 0 0 0 0 47 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 7 14 0 7 0 0 0 0 0 0 0 100 % D
% Glu: 14 7 47 40 7 7 7 0 7 0 0 0 0 0 0 % E
% Phe: 0 7 7 0 0 0 0 0 0 14 67 0 0 0 0 % F
% Gly: 0 7 7 7 0 7 54 0 0 0 0 0 0 54 0 % G
% His: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 7 0 0 0 14 0 7 0 0 0 54 0 0 0 % I
% Lys: 14 7 7 0 14 7 14 7 60 0 0 0 0 0 0 % K
% Leu: 0 60 14 0 0 0 0 0 0 7 0 0 80 0 0 % L
% Met: 0 7 0 0 0 0 0 0 0 34 0 0 20 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 7 14 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 7 7 7 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 47 0 7 0 0 7 0 7 20 0 0 0 0 0 0 % R
% Ser: 14 0 7 14 0 14 7 20 7 0 0 0 0 0 0 % S
% Thr: 0 0 0 7 14 47 0 0 7 20 0 0 0 0 0 % T
% Val: 14 0 0 0 20 0 0 27 0 27 0 47 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 27 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _