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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DPH2 All Species: 14.55
Human Site: T407 Identified Species: 22.86
UniProt: Q9BQC3 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BQC3 NP_001375.2 489 52083 T407 P E S E L W E T P D V S L I T
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_532611 487 51822 T405 P D S E L W D T P D V S L I T
Cat Felis silvestris
Mouse Mus musculus Q9CR25 489 52346 T407 P E S E L W D T P D V S L I S
Rat Rattus norvegicus Q568Y2 489 52306 T407 P E S E L W D T P D V S L I S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZKI2 477 52145 V393 A A E A I P D V S L I T G E M
Frog Xenopus laevis Q6DE00 478 52667 V396 S D A H H T D V S L I T G N L
Zebra Danio Brachydanio rerio A4QN59 498 55134 V408 T E E E T T D V S L I T G A L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650402 469 52077 P381 P E G R S F L P F D A A D I P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q09454 476 52936 E393 A E F A A F L E D K I E T E V
Sea Urchin Strong. purpuratus XP_786110 552 60545 R471 S L V T G K L R S L G T R E D
Poplar Tree Populus trichocarpa XP_002326199 496 54716 V405 E E A R F S F V Q G R Y V E D
Maize Zea mays NP_001146073 514 56668 C429 G V Y V E D N C P Q E N E E Q
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_191522 491 54825 G401 P R F S F F Q G G Y V E D H K
Baker's Yeast Sacchar. cerevisiae P32461 534 59757 A406 W V V D F R D A I D E I E Q N
Red Bread Mold Neurospora crassa Q7S5C0 602 65317 S502 W R T G K L V S H S R P M R M
Conservation
Percent
Protein Identity: 100 N.A. N.A. 88.3 N.A. 83.6 84.8 N.A. N.A. 47.4 44.3 38.7 N.A. 29.6 N.A. 29.8 35.5
Protein Similarity: 100 N.A. N.A. 91.6 N.A. 88.9 89.5 N.A. N.A. 60.3 61.1 56.6 N.A. 47.6 N.A. 48.2 51.2
P-Site Identity: 100 N.A. N.A. 86.6 N.A. 86.6 86.6 N.A. N.A. 0 0 13.3 N.A. 26.6 N.A. 6.6 0
P-Site Similarity: 100 N.A. N.A. 100 N.A. 100 100 N.A. N.A. 26.6 33.3 33.3 N.A. 40 N.A. 20 6.6
Percent
Protein Identity: 27 26 N.A. 26.2 25.6 24.7
Protein Similarity: 44.1 43.3 N.A. 45.2 40.8 37.2
P-Site Identity: 6.6 6.6 N.A. 13.3 6.6 0
P-Site Similarity: 20 13.3 N.A. 26.6 20 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 14 7 14 14 7 0 0 7 0 0 7 7 0 7 0 % A
% Cys: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % C
% Asp: 0 14 0 7 0 7 47 0 7 40 0 0 14 0 14 % D
% Glu: 7 47 14 34 7 0 7 7 0 0 14 14 14 34 0 % E
% Phe: 0 0 14 0 20 20 7 0 7 0 0 0 0 0 0 % F
% Gly: 7 0 7 7 7 0 0 7 7 7 7 0 20 0 0 % G
% His: 0 0 0 7 7 0 0 0 7 0 0 0 0 7 0 % H
% Ile: 0 0 0 0 7 0 0 0 7 0 27 7 0 34 0 % I
% Lys: 0 0 0 0 7 7 0 0 0 7 0 0 0 0 7 % K
% Leu: 0 7 0 0 27 7 20 0 0 27 0 0 27 0 14 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 14 % M
% Asn: 0 0 0 0 0 0 7 0 0 0 0 7 0 7 7 % N
% Pro: 40 0 0 0 0 7 0 7 34 0 0 7 0 0 7 % P
% Gln: 0 0 0 0 0 0 7 0 7 7 0 0 0 7 7 % Q
% Arg: 0 14 0 14 0 7 0 7 0 0 14 0 7 7 0 % R
% Ser: 14 0 27 7 7 7 0 7 27 7 0 27 0 0 14 % S
% Thr: 7 0 7 7 7 14 0 27 0 0 0 27 7 0 14 % T
% Val: 0 14 14 7 0 0 7 27 0 0 34 0 7 0 7 % V
% Trp: 14 0 0 0 0 27 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 7 0 0 0 0 0 0 7 0 7 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _